Reported are case histories of three infants with congenital malformations (including defective formation of the nose and hands) associated with ingestion of oral anticoagulants during the first trimester of pregnancy. (CL)

Examined were eight patients with cerebro-hepato-renal syndrome of Zellweger (associated with severe cerebral dysfunction, hypotonia and unusual appearance). (CL)

Laron's syndrome, characterized by severe dwarfism, high circulating levels of immunoreactive growth hormone, and failure to generate somatomedin after administration of human growth hormone, was studied in a boy 7 1/2 years of age. (MC)

The author reviews some of his observations regarding the responsibility of the physician caring for the hopelessly ill child and presents the resolutions proposed in 1974 by the adhoc committee on Ethics and Survival. (SB)

Presented were three case reports of patients, 8 to 18 years of age, who shared common features, such as obesity beginning in midchildhood, hypotonia, mental deficiency characteristic craniofacial appearance (antimongoloid slant, open mouth, or prominent central incisors), oral and ocular anomalies, and tapering extremities with narrow hands and…

Intelligence and speech-language development of eight children (3.6 to 11.6 years old) with classic galactosemia were assessed by standardized tests. Each of the children had delays of early speech difficulties, and all but one had language disorders in at least one area. Available from: Journal of Pediatrics, C.V. Mosby Co., 11830 Westline…

Discussed are clinical manifestations, potential fetal damage, and prevention of congenital rubella. (CL)