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de Jong, Valentijn M. T.; Moons, Karel G. M.; Riley, Richard D.; Tudur Smith, Catrin; Marson, Anthony G.; Eijkemans, Marinus J. C.; Debray, Thomas P. A. – Research Synthesis Methods, 2020
Many randomized trials evaluate an intervention effect on time-to-event outcomes. Individual participant data (IPD) from such trials can be obtained and combined in a so-called IPD meta-analysis (IPD-MA), to summarize the overall intervention effect. We performed a narrative literature review to provide an overview of methods for conducting an…
Descriptors: Meta Analysis, Intervention, Randomized Controlled Trials, Guidelines
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Engle, Jennifer A.; Smith, Mary Lou – Neuropsychologia, 2010
Epilepsy is frequently associated with attention and memory problems. In adults, lateralization of seizure focus impacts the type of memory affected (left-sided lesions primarily impact verbal memory, while right-sided lesions primarily impact visual memory), but the relationship between seizure focus and the nature of the memory impairment is…
Descriptors: Epilepsy, Memory, Attention, Neurological Impairments
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Villeneuve, Nathalie; Pinton, Florence; Bahi-Buisson, Nadia; Dulac, Olivier; Chiron, Catherine; Nabbout, Rima – Developmental Medicine & Child Neurology, 2009
Aim: We observed a dramatic response to the ketogenic diet in several patients with highly refractory epilepsy whose seizure frequency had recently worsened. This study aimed to identify whether this characteristic was a useful indication for the ketogenic diet. Method: From the 70 patients who received the ketogenic diet during a 3-year period at…
Descriptors: Symptoms (Individual Disorders), Comparative Analysis, Epilepsy, Seizures