Meta-analyses are systematic summaries of research that use quantitative methods to find the mean effect size (standardized mean difference) for interventions. Critics of meta-analysis point out that such analyses can conflate the results of low- and high-quality studies, make improper comparisons and result in statistical noise. All these…

Network meta-analysis is a popular method to synthesize the information obtained in a systematic review of studies (e.g., randomized clinical trials) involving subsets of multiple treatments of interest. The dominant method of analysis employs within-study information on treatment contrasts and integrates this over a network of studies. One…

Most evaluators have embraced the goal of evidence-based practice (EBP). Yet, many have criticized EBP review systems that prioritize randomized control trials and use various criteria to limit the studies examined. They suggest this could produce policy recommendations based on small, unrepresentative segments of the literature and recommend a…