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Merschbaecher, Katja; Hatko, Lucyna; Folz, Jennifer; Mueller, Uli – Learning & Memory, 2016
Acetylation of histones changes the efficiency of the transcription processes and thus contributes to the formation of long-term memory (LTM). In our comparative study, we used two inhibitors to characterize the contribution of different histone acetyl transferases (HATs) to appetitive associative learning in the honeybee. For one we applied…
Descriptors: Inhibition, Long Term Memory, Cognitive Processes, Comparative Analysis
Luque, David; Moris, Joaquin; Orgaz, Cristina; Cobos, Pedro L.; Matute, Helena – Psychological Record, 2011
Backward blocking (BB) and interference between cues (IbC) are cue competition effects produced by very similar manipulations. In a standard BB design, both effects might occur simultaneously, which implies a potential problem for studying BB. In the present study with humans, the magnitude of both effects was compared using a non-causal scenario…
Descriptors: Cues, Competition, Conditioning, Comparative Analysis
Ishii, Kiyoshi; Iguchi, Yoshio; Fukumoto, Kazuya; Nakayasu, Tomohiro – Learning and Motivation, 2008
Using a conditioned taste aversion procedure with rats as the subjects, two experiments examined the effect of presenting a conditioned stimulus (CS saccharin solution) in one context followed by an unconditioned stimulus (US LiCl) in a different context. Experiment 1 showed that animals which received the above-mentioned procedure (Group D)…
Descriptors: Stimuli, Animals, Conditioning, Experiments
Weible, Aldis P.; Oh, M. Matthew; Lee, Grace; Disterhoft, John F. – Learning & Memory, 2004
Cholinergic systems are critical to the neural mechanisms mediating learning. Reduced nicotinic cholinergic receptor (nAChR) binding is a hallmark of normal aging. These reductions are markedly more severe in some dementias, such as Alzheimer's disease. Pharmacological central nervous system therapies are a means to ameliorate the cognitive…
Descriptors: Conditioning, Animals, Eye Movements, Pharmacology
Isiegas, Carolina; Stein, Joel; Hellman, Kevin; Hannenhalli, Sridhar; Abel, Ted; Keeley, Michael B.; Wood, Marcelo A. – Learning & Memory, 2006
Classical fear conditioning requires the recognition of conditioned stimuli (CS) and the association of the CS with an aversive stimulus. We used Affymetrix oligonucleotide microarrays to characterize changes in gene expression compared to naive mice in both the amygdala and the hippocampus 30 min after classical fear conditioning and 30 min after…
Descriptors: Fear, Genetics, Stimuli, Animals