Millions of people do not have access to clean drinking water; thus, cost-efficient water treatment systems are vital. Chemists, environmentalists, technicians, and engineers will be the professionals making breakthroughs in this industry. This laboratory experiment aims to introduce undergraduate students to the removal of pollutants from water…

Protein PEGylation refers to the covalent binding of polyethylene glycol (PEG) moieties to a protein and has been increasingly applied, mainly in the biopharmaceutical industry. This technique may increase bioavailability and stability by decreasing immunogenicity and proteolytic attack. Given the industrial interest and the relevance of this…

The practical two-step synthesis of 1-phenylthiourea is reported here as an undergraduate experiment for the organic synthesis laboratory. The reactions involved in 1-phenylthiourea preparation are very useful didactic examples to illustrate concepts relating to carbonyl substitution and addition, the effect of pH on solubility of organic…

There has been dramatic growth in interest and research regarding organic photochromism in recent decades. Despite this, the topic is seldom addressed in the undergraduate chemistry curriculum. Herein, we present a straightforward and robust experiment for the second semester organic chemistry laboratory curriculum which combines multistep…

One of the main topics of elementary physics is the idea that every material is composed of "little particles that move around in perpetual motion, attracting each other when they are a little distance apart, but repelling upon being squeezed into one other." These particles could be atoms or molecules. Atoms are the smallest part into…

Electrochemical and spectroelectrochemical techniques are very important for characterizing energy materials. In the search for new sources of renewable energy, water splitting for hydrogen production and CO[subscript 2] reduction is attracting significant attention. These applications require efficient and durable catalysts and a detailed…

An ordinary soap bubble immersed in a pure carbon-dioxide atmosphere, created e.g. by sublimating chunks of dry ice (solid CO[subscript 2]), will expand within a few minutes to a volume exceeding the original one with a factor of almost ten. Considering that the bubble simultaneously experiences a cooling of ~30 ?C one would perhaps expect a tiny…

A fast, operationally simple, and reproducible synthetic protocol for anthraquinone dyes (AQDs), suitable for upper-division undergraduate industrial and organic chemistry laboratory courses, has been developed. This experiment is composed of three stages; the first step deals with the synthesis of AQDs, followed by a purification step, and…

A novel undergraduate analytical chemistry experiment involving the identification and quantification of linalool in essential oils was developed. The experiment uses the internal standard method with headspace solid phase microextraction (SPME) and gas chromatography--mass spectrometry (GC-MS). This method is applicable to any linalool-containing…

Cola beverages are widely consumed and popular among students; they can be used as safe reagents to replace toxic chemical dyes. In this study, a safe and improved experiment is described, which successfully demonstrates Beer's law and adsorption process using activated carbon as the adsorbent and cola as the adsorbate. The results of this study…

An introductory normal phase column chromatography experiment is described and evaluated for second year undergraduate chemistry laboratory class. The experiment involves a nucleophilic substitution yielding a crude mixture of reactant and one product, both of which are brightly colored and contrasting, creating a clearly visual separation when…

A drug discovery project has been successfully implemented in an advanced undergraduate organic chemistry laboratory. In the laboratory, a five-step synthetic sequence is used to prepare five analogues of 13-phenyl-1-tridecanol. These compounds are key precursors in the synthesis of 2-oxo-14-phenyltetradecanes. This class of compounds, isolated…

Plant-derived natural products are an important source of potential medicines and continue to have a major impact on the drug discovery process. Natural product discovery assignments provide an opportunity to present various experimental techniques to undergraduate students in introductory medicinal chemistry. This assignment was developed to…

A community-engaged learning experiment was developed for an introductory analytical chemistry course at the University of Toronto Scarborough in collaboration with Campus Farm. The experiment introduced students to the application of analytical techniques to studying environmental samples. More specifically, students investigated the potential of…

Experiments involving electrochemical cells are of great pedagogical value for learners of introductory chemistry. This paper discusses an improved experimental kit made from a 24-well cell culture plate and a 3D-printed scaffold. The current design focuses not only on the accuracy of the result but also on the intuitiveness of the wiring work and…