This paper examines how some fundamental mechanisms of nervous system activity can explain human information processing and the acquisition of knowledge and provides additional theoretical support for constructivist applications to science education reform. The implications for scientific epistemology and conceptual change processes in science…

Explores the significant findings that have emerged from research about the human brain regarding the importance of creating a brain-compatible learning environment. Presents eight components of a brain-compatible learning environment: absence of threat, meaningful content, choices, adequate time, enriched environment, collaboration, immediate…

Background: Brain morphology and physiological measures in schizophrenia have yielded inconsistent results. This may be due in part to difficulties in ascertaining precisely to what degree each measure deviates from its genetically and environmentally determined potential level. We attempted to surmount this problem in a paradigm involving…

Acetylcholine release in sensory neocortex contributes to higher-order sensory function, in part by activating nicotinic acetylcholine receptors (nAChRs). Molecular studies have revealed a bewildering array of nAChR subtypes and cellular actions; however, there is some consensus emerging about the major nAChR subtypes and their functions in…

Fetal and infant rats can learn to avoid odors paired with illness before development of brain areas supporting this learning in adults, suggesting an alternate learning circuit. Here we begin to document the transition from the infant to adult neural circuit underlying odor-malaise avoidance learning using LiCl (0.3 M; 1% of body weight, ip) and…

This paper reviews the existing empirical research on autism in the context of the semiotic theories of Charles S. Peirce. His ideas of the generalized logic of relations are seen as explaining the unusual associations (or lack thereof) in autism. Concepts of "indices" or signs singling out distinct objects, and "adinity" or…

This review of the literature provides summaries of the genetic, neurophysiological, and biochemical approaches to understanding autism, with special reference to neuroanatomic, cognitive, and neuropsychological studies of this disorder. Available instruments for the assessment of autism and various treatment alternatives including drug therapy,…

Recently, knowledge of the mechanisms of visual-spatial attention has improved due to studies employing single cell recording with alert monkeys and studies using performance analysis of neurological patients. These studies suggest that a complex neural network including parts of the posterior parietal lobe and midbrain are involved in covert…

The brain sciences and education is the topic for this yearbook volume, which is divided into five parts. Part one consists of an introduction to the brain sciences that is a primer on the neuroanatomy, neurochemistry, and neurophysiology of the brain. Part two contains chapters on some of the basic processes of the brain: attention, cognition,…

Soviet neuropsychologist Sokolov's notions of tonic and phasic orienting responses and of defense responses are examined for relevance to individual information processing. The phasic orienting response provides an index to attention and to information demands generated by the cerebral cortex. The sum of orienting responses elicted by a message…

Incomplete intersensory integration development in schizophrenic children appears to be an underlying source of symptom expression and formation which usually fails to improve with age. (SB)

Reviews cases which support the view that parts of the left hemisphere control languages, no matter how it is expressed, while right-side regions are involved only in skilled nonlinguistic movements and perceptions. Compares recent findings with previously held theories. (ML)

Discusses a theory suggesting that thoughts, feelings, dreams, and other workings of the mind are produced by chemical and electrical activity in the networks of nerve cells that make up the bulk of the brain. Opinions of a neuroscientist, anatomist, cognitive scientist, philosopher of science, and a biophysicist are provided. (BC)

Discusses current learning theories, indicating that though many psychologists and ethologists now agree on using a mechanistic approach, some linguists doubt its adequacy. Implications of research on the mollusk "Aplasia" to understand the learning process are included. (JN)

Intended for pediatricians, the article considers aspects of diagnosis and treatment of learning problems including definitions and documentation, the examination, developmental lag, intelligence and psychometry, reversals, serial ordering, cognitive processes in reading, and hyperactivity. (DB)