Successful episodic memory requires binding of event details across spatial and temporal gaps. The neural processes underlying mnemonic binding, however, are not fully understood. Moreover, although acute stress is known to modulate memory, if and how stress changes mnemonic integration across time and space is unknown. To elucidate these issues,…

Recent semantic space models learn vector representations for word meanings by observing statistical redundancies across a text corpus. A word's meaning is represented as a point in a high-dimensional semantic space, and semantic similarity between words is quantified by a function of their spatial proximity (typically the cosine of the angle…

Three source-memory experiments were conducted with Spanish-English bilinguals and monolingual English speakers matched on age, education, nonverbal cognitive ability and socioeconomic status. Bilingual language proficiency and dominance were assessed using standardized objective measures. In Experiment 1, source was manipulated visuo-spatially,…

Using a combination of eye tracking and fMRI in a contextual cueing task, we explored the mechanisms underlying the facilitation of visual search for repeated spatial configurations. When configurations of distractors were repeated, greater activation in the right hippocampus corresponded to greater reductions in the number of saccades to locate…

The ability to learn visual-phonological associations is a unique predictor of word reading, and individuals with developmental dyslexia show impaired ability in learning these associations. In this study, we compared developmentally dyslexic and nondyslexic adults on their ability to form cross-modal associations (or "bindings") based…

How does the brain learn to recognize an object from multiple viewpoints while scanning a scene with eye movements? How does the brain avoid the problem of erroneously classifying parts of different objects together? How are attention and eye movements intelligently coordinated to facilitate object learning? A neural model provides a unified…

A quantitative computational theory of the operation of the CA3 system as an attractor or autoassociation network is described. Based on the proposal that CA3-CA3 autoassociative networks are important for episodic or event memory in which space is a component (place in rodents and spatial view in primates), it has been shown behaviorally that the…

Nurr1 expression is up-regulated in the brain following associative learning experiences, but its relevance to cognitive processes remains unclear. In these studies, rats initially received bilateral hippocampal infusions of control or antisense oligodeoxynucleotides (ODNs) 1 hour prior to training in a holeboard spatial discrimination task. Such…

A word may mean different things in different contexts. The current study explored the changing denotations of spatial terms, focusing on how the distance inferred from a spatial description varied as a function of the size of the objects being spatially related. We examined both terms that explicitly convey distance (i.e., topological terms such…

Study of a one-year-old's earliest use of prepositions found that spatial oppositions ("up-down") were learned first, and used in non-prepositional senses prior to prepositional usage. "With,""by,""to,""for,""at," and "of" were learned later and used to express case relationships and more often misused and omitted than the earlier-learned…