A meta-analysis was performed to evaluate the possible association between maternal alcohol drinking during pregnancy and autism spectrum disorder (ASD) in offspring. Twelve datasets from five observational studies were included. Results showed that maternal alcohol drinking during pregnancy was not independently associated with ASD (risk ratio:…

In the United States, most mothers work during pregnancy. Yet, until the passage of the Pregnant Workers Fairness Act in 2022, pregnant employees did not have a right to reasonable accommodations to work under safe conditions. This law is expected to increase employment among pregnant women, making it critical to understand the effects of work…

Autism spectrum disorder (ASD) is a developmental disorder characterised by deficits in social interactions and communication, with stereotypical and repetitive behaviours. Recent evidence suggests that maternal immune dysregulation may predispose offspring to ASD. Independent samples t-tests revealed downregulation of IL-17A concentrations in…

This study aimed to verify the course of maternal anxiety disorders and its impact on child development of toddlers. This is a cohort study that followed 497 pregnant adolescents who received antenatal care in the public health service in a southern city in Brazil. We assessed maternal anxiety disorders during gestation, postpartum, and when…

The proposed study sought to investigate whether maternal experiences of racial discrimination and gendered racial stress are associated with offspring executive functioning. Total 266 Black mother-child pairs in the United States were assessed from pregnancy through child age of 4 years. We hypothesized that children whose mothers reported higher…

Researchers and practitioners need robust measurement tools for evaluating knowledge of child development to better support parents and their children during pregnancy and the transition to parenthood. We addressed this need by evaluating the psychometric properties of the Domains of Development Instrument (DoDI) for measuring knowledge of…

Background: Drawing on the family stress model (Conger and Donnellan in Ann Rev Psychol 58:175-199, 2007. https://doi-org.bibliotheek.ehb.be/10.1146/annurev.psych.58.110405.085551), parenting programs typically support caregivers' nurturing and cognitively stimulating practices to mitigate the effects of poverty on child development, with small-to-moderate…

Prenatal and postpartum depression are highly prevalent worldwide, and emerging evidence suggests they contribute to impairments in children's executive functions. Studies of maternal depression, however, have focused on the postpartum and postnatal periods with relatively less consideration of prenatal influences on child development. This study…

Prenatal folate and vitamin B[subscript 12] status have been linked to child neuropsychological development, but less is known about maternal genetic influences on this association. We conducted an exploratory longitudinal study of 181 mother--child pairs to assess whether maternal MTHFR 677C>T genotype modifies the association between maternal…

There is great opportunity in pediatric primary care to lay the foundation for lifelong health and well-being during the critical period from infancy to early childhood. However, many of these opportunities are missed, particularly for the most vulnerable children. The challenges to equitable, universal developmental and behavioral screening in…

The association of autism spectrum disorder (ASD) with self-reported maternal cannabis use from 3 months pre-conception to delivery ("peri-pregnancy") was assessed in children aged 30-68 months, born 2003 to 2011. Children with ASD (N = 1428) were compared to children with other developmental delays/disorders (DD, N = 1198) and…

Children of teen mothers have worse academic, labor market, and behavioral outcomes in the United States, but it is not clear whether these poor outcomes are caused by having a young mother or driven by selection into teen motherhood. Understanding the reasoning behind poor child outcomes is important for designing effective policies to improve…

The effectiveness of Promoting First Relationships (PFR), a 10-week home visiting program with video feedback, was tested in a randomized controlled trial involving 252 mothers and their 8- to 12-week-old infants. Mothers were eligible if they initiated treatment after mental health screening (depression, anxiety, posttraumatic stress disorder…

Identifying children at the risk of developmental delay can improve their long-term prognosis. In this case--control study, mothers and infants aged 6--18 months referred to healthcare centres affiliated with Qazvin University of Medical Sciences were recruited from August to December 2017. The sample size consisted of 197 individuals in…

Opioid use during pregnancy is associated with suboptimal pregnancy outcomes. Little is known about child neurodevelopmental outcomes. We examined associations between maternal opioid prescriptions preconception to delivery (peri-pregnancy) and child's risk of ASD, developmental delay/disorder (DD) with no ASD features, or ASD/DD with autism…