The prevalence of refractive error and ocular disorders among infants and young children with severe behavioral problems and developmental disorders is not well defined, particularly in developing countries. We performed a retrospective review of ophthalmic examinations performed during a National Institutes of Health--funded cohort study of very…

The family-centered medical home describes an approach to providing comprehensive primary care. Research advances in developmental neuroscience, genetics, and epigenetics offer a framework for understanding the dynamic process of brain development. It is this process that sets the life-course trajectory for an individual; in turn, a child's…

Chromosomal microarray analysis (CMA) has emerged as a powerful new tool to identify genomic abnormalities associated with a wide range of developmental disabilities including congenital malformations, cognitive impairment, and behavioral abnormalities. CMA includes array comparative genomic hybridization (CGH) and single nucleotide polymorphism…

There is a very substantial literature over the past 50 years on the advantages of early detection and intervention on the cognitive, communicative, and social-emotional development of infants and toddlers at risk for developmental delay due to premature birth or social disadvantage. Most of these studies excluded children with severe delays or…

Presents suggestions to help school nurses intervene on behalf of students who demonstrate signs of Pervasive Developmental Disorders (PDD) and other autism-related syndromes. The paper describes autism and Asperger's syndrome and discusses how to help students with PDD. Two sidebars present PDD subtypes and signs and symptoms of Asperger's…

Explains characteristics of attention deficit hyperactivity disorder (ADHD): delay in self-regulation; living in the moment; difficulty remaining focused; lag in social development; and the positive characteristics of intuition, spontaneity, energy, creativity, and artistic skills. Sidebars discuss a neurobiological understanding of ADHD and tips…

Reviews the behavioral, cognitive, and other psychological features of Prader-Willi Syndrome (PWS), exploring their relationships to known genetic mechanisms. PWS is a genetic developmental disability characterized by a group of specific behavioral features, including an insatiable appetite. The article briefly touches on PWS-related research at…

This study, which applied an instructional model based on Piaget's theory of cognitive development, pragmatics theory of language development, and Mahler's theory of development of interpersonal relationships, found that 49 preschool children with autism did not make less progress than a comparison group of 27 children with other…

Raises concerns about the failure of mental health service providers to address the psycho-developmental needs of people with mental retardation, especially incarcerated individuals with severe behavior disturbances and both mental illness and mental retardation. A "flight from developmental theory" is seen in most service providers to this…

The manual is intended to provide preschool educators who work with exceptional children with both theoretical background and practical guidance in teaching children with attentional deficit disorders, oppositional disorders, conduct disorders, autism, developmental learning disorders, childhood depression, borderline personality disorders, and…

Key to the mission of the National Institute of Child Health and Human Development (NICHD) is answering fundamental questions about how a single fertilized cell eventually develops into a fully functional adult human being and how a multitude of genetic and environmental factors influence that process. This document details part of NICHD's…