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Direct linkScerif, Gaia; Longhi, Elena; Cole, Victoria; Karmiloff-Smith, Annette; Cornish, Kim – Journal of Child Psychology and Psychiatry, 2012
Background: Fragile X syndrome (FXS) is an early diagnosed monogenic disorder, associated with a striking pattern of cognitive/attentional difficulties and a high risk of poor behavioural outcomes. FXS therefore represents an ideal model disorder to study prospectively the impact of early attention deficits on behaviour. Methods: Thirty-seven boys…
Descriptors: Visual Stimuli, Children, Males, Genetic Disorders
Moss, Jo; Howlin, Patricia; Magiati, Iliana; Oliver, Chris – Journal of Child Psychology and Psychiatry, 2012
Background: The prevalence of autism spectrum disorder (ASD) symptomatology is comparatively high in Cornelia de Lange syndrome (CdLS). However, the profile and developmental trajectories of these ASD characteristics are potentially different to those observed in individuals with idiopathic ASD. In this study we examine the ASD profile in CdLS in…
Descriptors: Autism, Pervasive Developmental Disorders, Genetic Disorders, Mental Retardation
Evidence for Shared Genetic Risk between ADHD Symptoms and Reduced Mathematics Ability: A Twin Study
Greven, Corina U.; Kovas, Yulia; Willcutt, Erik G.; Petrill, Stephen A.; Plomin, Robert – Journal of Child Psychology and Psychiatry, 2013
Background: Attention-deficit/hyperactivity disorder (ADHD) symptoms and mathematics ability are associated, but little is known about the genetic and environmental influences underlying this association. Methods: Data came from more than 6,000 twelve-year-old twin pairs from the UK population-representative Twins Early Development Study. Parents…
Descriptors: Attention Deficit Hyperactivity Disorder, Symptoms (Individual Disorders), Genetic Disorders, Environmental Influences
Dykens, Elisabeth M.; Roof, Elizabeth – Journal of Child Psychology and Psychiatry, 2008
Background: Some behavioral features of Prader-Willi syndrome (PWS) are associated with the major genetic subtypes of this disorder. While most agree that those with maternal uniparental disomy (UPD) have a distinctive cognitive and psychiatric profile, findings are more controversial regarding possible differences among persons who vary in…
Descriptors: Genetic Disorders, Developmental Disabilities, Caregivers, Behavior Problems
Hessl, David; Glaser, Bronwyn; Dyer-Friedman, Jennifer; Reiss, Allan L. – Journal of Child Psychology and Psychiatry, 2006
Objective: To examine the association between limbic-hypothalamic-pituitary-adrenal (L-HPA) axis reactivity and social behavior in children with fragile X syndrome (FXS). Method: Salivary cortisol changes and concurrent anxiety-related behaviors consistent with the behavioral phenotype of FXS were measured in 90 children with the fragile X full…
Descriptors: Stress Variables, Siblings, Nonverbal Communication, Social Behavior
Rietveld, M. J. H.; Hudziak, J. J.; Bartels, M.; Beijsterveldt, C. E. M.; Boomsma, D. I. – Journal of Child Psychology and Psychiatry, 2004
Background: Twin studies of childhood behavior problems support the conclusion that individual differences in impulsivity, hyperactivity, and inattention are largely due to genetic influences. Non-genetic variation is due to environmental influences that are unique to the individual, and possibly to rater contrast effects. In the present…
Descriptors: Check Lists, Twins, Behavior Problems, Structural Equation Models
