Research questions regarding how, for whom, and where a treatment achieves its effect on an outcome have become increasingly valued in substantive research. Such questions can be answered by causal moderated mediation analysis, which assesses the heterogeneity of the mediation mechanism underlying the treatment effect across individual and…

A reproducibility crisis afflicts a wide range of scientific and social-scientific disciplines, from epidemiology to social psychology. Improper research techniques, lack of accountability, disciplinary and political groupthink, and a scientific culture biased toward producing positive results together have produced a critical state of affairs.…