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Dong, Willie K.; Greenough, William T. – Mental Retardation and Developmental Disabilities Research Reviews, 2004
Neuronal and nonneuronal plasticity are both affected by environmental and experiential factors. Remodeling of existing neurons induced by such factors has been observed throughout the brain, and includes alterations in dendritic field dimensions, synaptogenesis, and synaptic morphology. The brain loci affected by these plastic neuronal changes…
Descriptors: Epilepsy, Mental Retardation, Autism, Brain
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Tuchman, Roberto – Mental Retardation and Developmental Disabilities Research Reviews, 2004
The efficacy of antiepileptic drugs (AEDs) and psychotropic medications in children with autism is limited to the treatment of seizures or to specific behaviors such as irritability, impulsivity, hyperactivity, repetitive behaviors, or aggression. The reliability and value of the available data--to determine the efficacy of these medications in…
Descriptors: Epilepsy, Narcotics, Autism, Seizures