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Direct linkBarger, Brian D.; Campbell, Jonathan; Simmons, Christina – Journal of Intellectual & Developmental Disability, 2017
Background: The strength of the relationship between epilepsy and regression in autism spectrum disorder (ASD) has been much discussed but is currently unclear. Methods: The authors conducted 2 meta-analyses of published studies to determine if children with ASD who experience regression (ASD-R) epilepsy are more likely to have epilepsy or…
Descriptors: Autism, Pervasive Developmental Disorders, Epilepsy, Diagnostic Tests
Wong, Virginia C. N.; Fung, Cecilia K. Y.; Wong, Polly T. Y. – Journal of Autism and Developmental Disorders, 2014
Data from 1,261 Chinese Autistic Spectrum Disorder (ASD) patients were evaluated and categorized into dysmorphic (10.79%) and non-dysmorphic groups (89.21%) upon physical examination by the presence of dysmorphic features. Abnormal MRI/CT result, IQ scores and epilepsy were significantly associated with the dysmorphic group of ASD children.…
Descriptors: Foreign Countries, Pervasive Developmental Disorders, Autism, Classification
Edens, Anna C.; Lyons, Michael J.; Duron, Reyna M.; DuPont, Barbara R.; Holden, Kenton R. – Developmental Medicine & Child Neurology, 2011
We present two phenotypically similar females with Xp duplication who have autism and epilepsy. Case 1 is a 14-year-old Honduran female with autism and medically refractory complex partial, secondarily generalized epilepsy. Case 2 is a 3-year-old Austrian female with autism and medically refractory complex partial epilepsy. Both patients also…
Descriptors: Epilepsy, Females, Patients, Autism
Beaudet, Arthur L. – Child Development, 2013
Chromosomal microarray analysis (CMA) has emerged as a powerful new tool to identify genomic abnormalities associated with a wide range of developmental disabilities including congenital malformations, cognitive impairment, and behavioral abnormalities. CMA includes array comparative genomic hybridization (CGH) and single nucleotide polymorphism…
Descriptors: Genetics, Genetic Disorders, Developmental Disabilities, Identification
Garbern, James Y.; Neumann, Manuela; Trojanowski, John Q.; Lee, Virginia M.-Y.; Feldman, Gerald; Norris, Joy W.; Friez, Michael J.; Schwartz, Charles E.; Stevenson, Roger; Sima, Anders A. F. – Brain, 2010
We have studied a family with severe mental retardation characterized by the virtual absence of speech, autism spectrum disorder, epilepsy, late-onset ataxia, weakness and dystonia. Post-mortem examination of two males revealed widespread neuronal loss, with the most striking finding being neuronal and glial tau deposition in a pattern reminiscent…
Descriptors: Severe Mental Retardation, Mental Retardation, Autism, Alzheimers Disease
Malow, Beth A. – Mental Retardation and Developmental Disabilities Research Reviews, 2004
The purpose of this review article is to describe the clinical data linking autism with sleep and epilepsy and to discuss the impact of treating sleep disorders in children with autism either with or without coexisting epileptic seizures. Studies are presented to support the view that sleep is abnormal in individuals with autistic spectrum…
Descriptors: Epilepsy, Autism, Seizures, Sleep
McVicar, Kathryn A.; Shinnar, Shlomo – Mental Retardation and Developmental Disabilities Research Reviews, 2004
The Landau-Kleffner syndrome (LKS) and electrical status epilepticus in slow wave sleep (ESES) are rare childhood-onset epileptic encephalopathies in which loss of language skills occurs in the context of an epileptiform EEG activated in sleep. Although in LKS the loss of function is limited to language, in ESES there is a wider spectrum of…
Descriptors: Language Skill Attrition, Pathology, Language Skills, Autism
