Histone acetylation, catalyzed by e, has emerged as a promising therapeutic strategy in Alzheimer's disease (AD). By longitudinally characterizing spatial memory at 3, 6, and 9 mo of age, we show that acute activation and inhibition of the histone acetyltransferase PCAF remediated memory impairments in 3xTG-AD mice in an age-related bidirectional…

The widespread adoption of mobile technologies has exacerbated their utilization in educational environments. Multitasking in the classroom is a common practice and deserves further investigation to understand its antecedents. Yet, rare studies have addressed this issue based on the theory of planned behavior framework. To this end, the current…

During the last decades, global interest in learning English as a foreign language has increased, encouraging countries to include it in school education. This trend was followed by the Chilean Ministry of Education, which suggests teaching English based on a communicative approach starting in early childhood education. To foster students'…

Purpose: Language production, a dynamic process involving real-time language processing, is crucial for children's language and communication development. To explore the early development of children's real-time language production, this study investigated Chinese preschool children's pausing strategies in narratives and their associations with…

Metacognition and self-regulated learning (SLR) have been advocated by many and have significant support being seen as a potentially effective and low cost way of impacting learning. Fundamentally, the underlying supposition is that metacognition and SRL are important to learning, and thus raise attainment, and various studies have established…

Expressive writing (EW), or writing about one's thoughts and feelings, has been posited to reduce the working memory (WM) load that pressure and anxiety can impose on test-takers. The mechanisms of EW are far from clear, however, and social and developmental questions about its role in shaping children's engagement with academic contexts remain.…

Forty-two adolescents with Down syndrome (DS) ages 10 to 21 years completed a battery of language and phonological memory measures twice, 2 years apart. Individual differences were highly stable across two years. Receptive vocabulary scores improved, there was no change in receptive or expressive grammar scores, and nonword repetition scores…

We used structural equation modeling in the Early Childhood Longitudinal Study--Kindergarten Cohort (N = 17,020) to explore the influence of having an older sibling on kindergarten-age focal children's cognitive self-regulation. In model 1, we tested how having a sibling who is generally older than the focal child contributes to the focal child's…

Multiple cognitive skills support the acquisition of proficient reading skills. Higher order processing abilities allowing the engagement and integration of multiple ideas collectively referred to as executive functions may be particularly important in reading comprehension. In the present study, 39 Danish school age children completed executive…

Across multiple schools and sites, the impact of grade-at-intervention was evaluated for children at risk or meeting criteria for reading disabilities. A multiple-component reading intervention with demonstrated efficacy was offered to small groups of children in 1st, 2nd, or 3rd grade. In a quasi-experimental design, 172 children received the…

Recent studies suggest that working memory training may benefit older adults; however, findings regarding training and transfer effects are mixed. The current study aimed to investigate the effects of a process-based training intervention in a diverse sample of older adults and explored possible moderators of training and transfer effects. For…

Autism Spectrum Disorders (ASD) are associated with abnormalities in face memory, which evidence suggests has a protracted development through adolescence. The development of face memory in people with and without ASD, from 9 to 29 years old, was examined using the Cambridge Face Memory Test (CFMT). Results indicate that the developmental…

Aim: There is a lack of investigation into the functional developmental profile of children with Down syndrome. On the basis of current international health paradigms, the purpose of this study was to assess the developmental profile of these children. Method: Sixty children (33 males, 27 females) with Down syndrome (age range 6-16y; mean age 9y…

Accurate prediction of early childhood reading performance could help identify at-risk students, aid in the development of evidence-based intervention strategies, and further our theoretical understanding of reading development. This study assessed the validity of the Developmental Indicator for the Assessment of Learning (DIAL) language-based…

Objectives: To determine whether oral language, working memory, and social anxiety differentiate children with selective mutism (SM), children with anxiety disorders (ANX), and normal controls (NCs) and explore predictors of mutism severity. Method: Children ages 6 to 10 years with SM (n = 44) were compared with children with ANX (n = 28) and NCs…