Discussions of the primary literature are an important part of undergraduate education, and much work has been done to develop methods of integrating the literature into the curriculum. Examples include individual single-article discussion activities, literature-based courses, and regular journal club events. While many published examples focus on…

We describe a three-day advanced organic laboratory experience that includes the solid-phase synthesis of an unknown three amino acid polypeptide for junior/senior undergraduate chemistry majors. Students conduct a series of 1D and 2D NMR experiments (HSQC, HMBC, TOCSY) and analyze the data to identify the side chain residues of the peptide and…

While several engineering and science disciplines, including biology and environmental science, have greatly benefited from adopting a systems thinking approach, its extension to chemistry education is a much more recent advancement. The initial body of literature in this direction has largely surveyed the feasibility for systems thinking in…

TNT is both toxic and explosive, and therefore, the detection of TNT represents an environmental concern and a security concern. Dogs are often used for detection, but other methods are needed. This laboratory investigates a ruthenium bipyridine ([Ru(bpy)[subscript 3]][superscript 2+]) luminescence-based trinitrotoluene (TNT) sensor. Students will…

Research has shown that the use of practical examples in undergraduate education promotes the retention of historically underrepresented students in STEM majors and lowers achievement gaps within courses. Since many students of color and women aspire toward careers in healthcare and the pharmaceutical industry, efforts to incorporate medicinal…

A laboratory exercise for undergraduate advanced students of enzymology and biocatalysis is presented. Since enzyme assays can be quenched or continuous, this experiment compares the performance of two quenching agents for lactase, in a continuous setup. Enzymatic activity of [beta]-galactosidase ("Aspergillus oryzae") was determined…

Research has frequently demonstrated negative effects of placing students into developmental education, but very little inquiry has considered the impact of placing students into different levels of non-developmental coursework. The present study explored this issue within sequenced pairs of STEM gateway courses using doubly-robust propensity…

Students often experience science, technology, engineering, and mathematics (STEM) courses as competitive, weed-out spaces. Learning Assistants (LAs) have potential to improve students' experiences in these courses. Previously, we elucidated themes describing the impact of LAs on students' sense of STEM belonging and science-related confidence in…

Disparate grade outcomes across various axes of student identities are prevalent in introductory science, technology, engineering, and mathematics (STEM) courses, including in the biological sciences, yet few studies have examined outcome disparities in upper-division courses. Those that have present mixed findings. Rooted in a critical approach…

We examine students' challenges in determining the number of distinct many-particle stationary states for a system of noninteracting identical particles, focusing on how these insights guided the design, validation, and evaluation of a quantum interactive learning tutorial (QuILT) to aid students' understanding. Specifically, we focus on systems…

Recently, interest in understanding the prospects of virtual environments, specifically virtual reality laboratories (VR Lab) -- those that involve a first-person practica experience via a desktop computer or head-mounted display -- in science education has increased. Seemingly ingrained in the process of implementing a VR Lab is a supposition of…

Generative large language models (LLMs) like ChatGPT can quickly produce informative essays on various topics. However, the information generated cannot be fully trusted, as artificial intelligence (AI) can make factual mistakes. This poses challenges for using such tools in college classrooms. To address this, an adaptable assignment called the…

This article reports on the implementation of a CURE project in an upper-level analytical chemistry course to engage a larger number of students in research at a primarily undergraduate institution (PUI). The lab course syllabus was modified to provide students with an opportunity to experience the process of conducting research through a project…

Peer learning has become a central feature in many postsecondary classrooms. Many peer learning activities feature near-peer instructors who had previously completed the course and who later serve as peer leaders. There are relatively few examples of activities in which students in a course act as true peer instructors for their classmates. One…

One of the more difficult concepts introduced in the first-year undergraduate course, general chemistry, is that of chirality. Typically, left and right hands are the common, macroscopic objects of reference used to demonstrate the quality of being nonsuperimposable, followed by the use of a mirror and molecular models, to illustrate molecular…