The U.S. Environmental Protection Agency (EPA) was created in 1970 to protect human health and the environment. The year 2007 marks 10 years of concerted Federal effort to address children's environmental health risks as mandated by Executive Order 13045, Protection of Children from Environmental Health Risks and Safety Risks. Much of the agency's work is done in partnership with others and falls generally into three categories: outreach and education, science and research, and regulatory action. Through outreach and education, the agency works to train health care providers on the environmental causes or contributors to ill health in children, and it educates parents on how to protect their children from harmful exposures. Research in the last decade has documented many nuances about the effects of physical, chemical, and biological exposures on children's health. The agency strives to write policies and regulations that protect all children from exposure to harmful substances. This report captures much of the agency's work.