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Direct linkMizutani, Shosuke; Zhou, Yi; Tian, Yu-Shi; Takagi, Tatsuya; Ohkubo, Tadayasu; Hattori, Satoshi – Research Synthesis Methods, 2023
Meta-analysis of diagnostic test accuracy (DTA) is a powerful statistical method for synthesizing and evaluating the diagnostic capacity of medical tests and has been extensively used by clinical physicians and healthcare decision-makers. However, publication bias (PB) threatens the validity of meta-analysis of DTA. Some statistical methods have…
Descriptors: Meta Analysis, Diagnostic Tests, Accuracy, Publications
Petersen, Julie M.; Barrett, Malcolm; Ahrens, Katherine A.; Murray, Eleanor J.; Bryant, Allison S.; Hogue, Carol J.; Mumford, Sunni L.; Gadupudi, Salini; Fox, Matthew P.; Trinquart, Ludovic – Research Synthesis Methods, 2022
Systematic reviews and meta-analyses are essential for drawing conclusions regarding etiologic associations between exposures or interventions and health outcomes. Observational studies comprise a substantive source of the evidence base. One major threat to their validity is residual confounding, which may occur when component studies adjust for…
Descriptors: Bias, Meta Analysis, Etiology, Intervention
Jager, Nicolas W.; Newig, Jens; Challies, Edward; Kochskämper, Elisa; von Wehrden, Henrik – Research Synthesis Methods, 2022
Meta-analytical methods face particular challenges in research fields such as social and political research, where studies often rest primarily on qualitative and case study research. In such contexts, where research findings are less standardized and amenable to structured synthesis, the case survey method has been proposed as a means of data…
Descriptors: Social Sciences, Meta Analysis, Case Studies, Validity
Mathur, Maya B.; VanderWeele, Tyler J. – Research Synthesis Methods, 2021
Selective publication and reporting in individual papers compromise the scientific record, but are meta-analyses as compromised as their constituent studies? We systematically sampled 63 meta-analyses (each comprising at least 40 studies) in "PLoS One," top medical journals, top psychology journals, and Metalab, an online, open-data…
Descriptors: Periodicals, Peer Evaluation, Bias, Meta Analysis
Noma, Hisashi; Hamura, Yasuyuki; Sugasawa, Shonosuke; Furukawa, Toshi A. – Research Synthesis Methods, 2023
Network meta-analysis has played an important role in evidence-based medicine for assessing the comparative effectiveness of multiple available treatments. The prediction interval has been one of the standard outputs in recent network meta-analysis as an effective measure that enables simultaneous assessment of uncertainties in treatment effects…
Descriptors: Intervals, Meta Analysis, Evidence Based Practice, Comparative Analysis
Shi, Linyu; Chu, Haitao; Lin, Lifeng – Research Synthesis Methods, 2020
Publication bias threatens meta-analysis validity. It is often assessed via the funnel plot; an asymmetric plot implies small-study effects, and publication bias is one cause of the asymmetry. Egger's regression test is a widely used tool to quantitatively assess such asymmetry. It examines the association between the observed effect sizes and…
Descriptors: Bayesian Statistics, Meta Analysis, Effect Size, Publications
Gusenbauer, Michael; Haddaway, Neal R. – Research Synthesis Methods, 2020
Rigorous evidence identification is essential for systematic reviews and meta-analyses (evidence syntheses) because the sample selection of relevant studies determines a review's outcome, validity, and explanatory power. Yet, the search systems allowing access to this evidence provide varying levels of precision, recall, and reproducibility and…
Descriptors: Evidence, Databases, Meta Analysis, Validity
Suurmond, Robert; van Rhee, Henk; Hak, Tony – Research Synthesis Methods, 2017
We present a new tool for meta-analysis, "Meta-Essentials," which is free of charge and easy to use. In this paper, we introduce the tool and compare its features to other tools for meta-analysis. We also provide detailed information on the validation of the tool. Although free of charge and simple, "Meta-Essentials"…
Descriptors: Meta Analysis, Research Tools, Comparative Analysis, Validity
