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Direct linkJiang, Ziren; Cao, Wenhao; Chu, Haitao; Bazerbachi, Fateh; Siegel, Lianne – Research Synthesis Methods, 2023
A reference interval, or an interval in which a prespecified proportion of measurements from a healthy population are expected to fall, is used to determine whether a person's measurement is typical of a healthy individual. For a specific biomarker, multiple published studies may provide data collected from healthy participants. A reference…
Descriptors: Intervals, Computation, Meta Analysis, Measurement
Papadimitropoulou, Katerina; Stijnen, Theo; Dekkers, Olaf M.; le Cessie, Saskia – Research Synthesis Methods, 2019
The vast majority of meta-analyses uses summary/aggregate data retrieved from published studies in contrast to meta-analysis of individual participant data (IPD). When the outcome is continuous and IPD are available, linear mixed modelling methods can be employed in a one-stage approach. This allows for flexible modelling of within-study…
Descriptors: Meta Analysis, Outcome Measures, Hierarchical Linear Modeling, Sample Size
