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Harrison, Jason Gordon – ProQuest LLC, 2013
Quantum mechanical (QM) and molecular docking methods are used to probe systems of biological and synthetic interest. Probing interactions of nucleobases within proteins, and properly modeling said interactions toward novel nucleobase development, is extremely difficult, and of great utility in RNA interference (RNAi) therapeutics. The issues in…
Descriptors: Computation, Scientific Concepts, Research Methodology, Scientific Research