The purpose of this dissertation is to develop principles and strategies for and identify limitations of multisite cluster randomized trials in the context of partially and fully nested designs. In the first study, I develop principles of estimation, sampling variability, and inference for studies that leverage multisite designs within the context…

In basic regression discontinuity (RD) designs, causal inference is limited to the local area near a single cutoff. To strengthen the generality of the RD treatment estimate, a design with multiple cutoffs along the assignment variable continuum can be applied. The availability of multiple cutoffs allows estimation of a pooled average treatment…