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Felsenberg, Johannes; Dombrowski, Vincent; Eisenhardt, Dorothea – Learning & Memory, 2012
Protein degradation is known to affect memory formation after extinction learning. We demonstrate here that an inhibitor of protein degradation, MG132, interferes with memory formation after extinction learning in a classical appetitive conditioning paradigm. In addition, we find an enhancement of memory formation when the same inhibitor is…
Descriptors: Memory, Learning Processes, Role, Entomology
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Dirikx, Trinette; Hermans, Dirk; Vansteenwegen, Debora; Baeyens, Frank; Eelen, Paul – Learning & Memory, 2004
The present study investigated reinstatement of conditioned responses in humans by using a differential Pavlovian conditioning procedure. Evidence for reinstatement was established in a direct (fear rating) and in an indirect measure (secondary reaction time task) of conditioning. Moreover, the amount of reinstatement in the secondary reaction…
Descriptors: Stimuli, Fear, Classical Conditioning, Reaction Time
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Thompson, Laura; Wright, William G.; Hoover, Brian A.; Nguyen, Hoang – Learning & Memory, 2006
Much recent research on mechanisms of learning and memory focuses on the role of heterosynaptic neuromodulatory signaling. Such neuromodulation appears to stabilize Hebbian synaptic changes underlying associative learning, thereby extending memory. Previous comparisons of three related sea-hares (Mollusca, Opisthobranchia) uncovered interspecific…
Descriptors: Classical Conditioning, Memory, Associative Learning, Correlation
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Cheng, Jingjun; Feenstra, Matthijs G. P. – Learning & Memory, 2006
Combined activation of dopamine D1- and NMDA-glutamate receptors in the nucleus accumbens has been strongly implicated in instrumental learning, the process in which an individual learns that a specific action has a wanted outcome. To assess dopaminergic activity, we presented rats with two sessions (30 trials each) of a one-lever appetitive…
Descriptors: Rewards, Biochemistry, Nonverbal Learning, Animals
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Shors, Tracey J. – Learning & Memory, 2004
Stressful life events can have profound effects on our cognitive and motor abilities, from those that could be construed as adaptive to those not so. In this review, I discuss the general notion that acute stressful experience necessarily impairs our abilities to learn and remember. The effects of stress on operant conditioning, that is, learned…
Descriptors: Learning Processes, Operant Conditioning, Helplessness, Classical Conditioning