The purpose of the current study was to examine the role that personal resources (person-environment [PE] congruence and personality types associated with resilience) and work-family conflict (WFC) play in the sense of well-being (as reflected by burnout and life-satisfaction) of mothers of young children. A sample of 146 mothers holding demanding careers completed six questionnaires. Based on Baron and Kenny (1986), several regression analyses were conducted. The results indicated that PE congruence was not related to life satisfaction but was negatively related to burnout, a relationship fully mediated by both work-interferes-family (WIF) and family-interferes-work (FIW) conflict dimensions. Personality type was related to burnout and life-satisfaction (Resilients exhibited higher levels of well-being than both Undercontrollers and Overcontrollers), a relationship which was only partially mediated by WIF and FIW. Implications for career planning and counseling, particularly for women, are discussed. (Contains 3 tables.)