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de Winter, C. F.; Jansen, A. A. C.; Evenhuis, H. M. – Journal of Intellectual Disability Research, 2011
Background: Challenging behaviour is a major problem among people with intellectual disabilities. Physical factors may be an important cause. The aim of the present systematic review was to determine the physical conditions associated with challenging behaviour. Methods: A literature search was conducted in PubMed and the Cochrane systematic…
Descriptors: Mental Retardation, Behavior Problems, Physical Disabilities, Epilepsy
Gasca, C. Brun; Obiols, J. E.; Bonillo, A.; Artigas, J.; Lorente, I.; Gabau, E.; Guitart, M.; Turk, J. – Journal of Intellectual Disability Research, 2010
Background: Angelman syndrome (AS) is a neurodevelopmental disorder usually caused by an anomaly in the maternally inherited chromosome 15. The main features are severe intellectual disability, speech impairment, ataxia, epilepsy, sleep disorder and a behavioural phenotype that reportedly includes happy disposition, attraction to/fascination with…
Descriptors: Severe Mental Retardation, Profiles, Communication Skills, Adjustment (to Environment)
Braam, W.; Didden, R.; Smits, M.; Curfs, L. – Journal of Intellectual Disability Research, 2008
Background: While several small-number or open-label studies suggest that melatonin improves sleep in individuals with intellectual disabilities (ID) with chronic sleep disturbance, a larger randomized control trial is necessary to validate these promising results. Methods: The effectiveness of melatonin for the treatment of chronic sleep…
Descriptors: Epilepsy, Seizures, Caregivers, Sleep
Sajith, S. G.; Clarke, D. – Journal of Intellectual Disability Research, 2007
Background: Melatonin is used to treat sleep disorders in both children and adults with intellectual disability (ID), although it has no product license for such use. The evidence for its efficacy, potential adverse effects and drug interactions are reviewed in the context of prescribing to people with ID. Methods: A literature search was…
Descriptors: Adolescents, Sleep, Outcomes of Treatment, Normalization (Disabilities)

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