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Direct linkRoy, A.; Roy, M.; Deb, S.; Unwin, G.; Roy, A. – Journal of Intellectual Disability Research, 2015
Background: ASC (autism spectrum conditions) may result from a failure of striatal beta endorphins to diminish with maturation. Many symptoms of ASC resemble behaviours induced in animals or humans by opiate administration, including decreased socialisation, diminished crying, repetitive stereotypies, insensitivity to pain and motor hyperactivity.…
Descriptors: Autism, Pervasive Developmental Disorders, Drug Therapy, Behavior Problems
Richards, C.; Oliver, C.; Nelson, L.; Moss, J. – Journal of Intellectual Disability Research, 2012
Background: Autism spectrum disorder (ASD) has been identified as a risk marker for self-injurious behaviour. In this study we aimed to describe the prevalence, topography and correlates of self-injury in individuals with ASD in contrast to individuals with Fragile X and Down syndromes and examine person characteristics associated with self-injury…
Descriptors: Genetic Disorders, Conceptual Tempo, Topography, Incidence
Arron, K.; Oliver, C.; Moss, J.; Berg, K.; Burbidge, C. – Journal of Intellectual Disability Research, 2011
Background: Self-injurious and aggressive behaviours are reported as components of some behavioural phenotypes but there are few studies comparing across syndrome groups. In this study we examined the prevalence of these behaviours and the associated person characteristics in seven genetic syndromes. Methods: Questionnaire data on self-injury and…
Descriptors: At Risk Persons, Intervention, Incidence, Injuries
Richman, D. M.; Barnard-Brak, L.; Bosch, A.; Thompson, S.; Grubb, L.; Abby, L. – Journal of Intellectual Disability Research, 2013
Background: Presence of an autism spectrum disorder is a risk factor for development of self-injurious behaviour (SIB) exhibited by individuals with developmental disorders. The most salient SIB risk factors historically studied within developmental disorders are level of intellectual disability, communication deficits and presence of specific…
Descriptors: Predictor Variables, Risk, Self Destructive Behavior, Injuries
Ji, N. Y.; Capone, G. T.; Kaufmann, W. E. – Journal of Intellectual Disability Research, 2011
Background: The diagnostic validity of autism spectrum disorder (ASD) based on Diagnostic and Statistical Manual of Mental Disorders (DSM) has been challenged in Down syndrome (DS), because of the high prevalence of cognitive impairments in this population. Therefore, we attempted to validate DSM-based diagnoses via an unbiased categorisation of…
Descriptors: Check Lists, Autism, Hyperactivity, Down Syndrome
Oliver, C.; Sloneem, J.; Hall, S.; Arron, K. – Journal of Intellectual Disability Research, 2009
Background: Self-injurious behaviour is frequently identified as part of the behavioural phenotype of Cornelia de Lange syndrome (CdLS). We conducted a case-control study of the prevalence and phenomenology of self-injurious behaviour (SIB) in CdLS. Methods: A total of 54 participants with CdLS were compared with 46 individuals who were comparable…
Descriptors: Incidence, Mental Retardation, Injuries, Hyperactivity
