Mediation analysis in Single Case Experimental Designs (SCEDs) evaluates intervention mechanisms for individuals. Despite recent methodological developments, no clear guidelines exist for maximizing power to detect the indirect effect in SCEDs. This study compares frequentist and Bayesian methods, determining (1) minimum required sample size to…

A simulation study was conducted to examine the efficacy of nine frequently-used HOV tests, including Levene's tests with squared residuals and with absolute residuals, Brown and Forsythe (BF) test, Bootstrap BF test, O'Brien test, Z-variance test, Box-Scheffé (BS) test, Bartlett test, and Pseudo jackknife test under comprehensive simulation…

Cluster-randomized trials have been widely used to evaluate the treatment effects of interventions on student outcomes. When interventions are implemented by teachers, researchers need to account for the nested structure in schools (i.e., students are nested within teachers nested within schools). Schools usually have a very limited number of…

Multisite cluster randomized trials (MCRTs), in which, the intermediate-level clusters (e.g., classrooms) are randomly assigned to the treatment or control condition within each site (e.g., school), are among the most commonly used experimental designs across a broad range of disciplines. MCRTs often align with the theory that programs are…

We have entered an era in which scientific evidence increasingly informs research practice and policy. As there is an exponential increase in the use of single-case experimental designs (SCEDs) to evaluate intervention effectiveness, there is accumulating evidence available for quantitative synthesis. Consequently, there is a growing interest in…

Artificial neural networks (NN) can help researchers estimate propensity scores for quasi-experimental estimation of treatment effects because they can automatically detect complex interactions involving many covariates. However, NN is difficult to implement due to the complexity of choosing an algorithm for various treatment levels and monitoring…

Multivariate analysis of variance (MANOVA) is widely used to test the null hypothesis of equal multivariate means across 2 or more groups. MANOVA rests upon an assumption that error terms are independent of one another, which can be violated if individuals are clustered or nested within groups, such as schools. Ignoring such nesting can result in…

Optimal design of multisite randomized trials leverages sampling costs to optimize sampling ratios and ultimately identify more efficient and powerful designs. Past implementations of the optimal design framework have assumed that costs of sampling units are equal across treatment conditions. In this study, we developed a more flexible optimal…

The piecewise latent growth models (PWLGMs) can be used to study changes in the growth trajectory of an outcome due to an event or condition, such as exposure to an intervention. When there are multiple outcomes of interest, a researcher may choose to fit a series of PWLGMs or a single parallel-process PWLGM. A comparison of these models is…