A study examined rates of labor induction using pitocin in 41 boys with autism and 25 matched controls with either typical development or mental retardation. There were no differences in pitocin induction rates as a function of either diagnostic group (autism vs. control) or IQ level (average vs. subaverage range). (Contains references.)…

This study compared 29 females with Turner syndrome and 21 females with fragile X syndrome (ages 6-22) on a videotaped role-play interaction with 34 females in a comparison group. Three of eight behavioral measures of social skills differentiated the participant groups. Fragile-X subjects required more time to initiate interactions and Turner…

Comparison of 28 young children with autism, 29 children with other developmental disabilities, and 28 typical children found that autistic children were significantly less compliant with parental prohibitions than were control groups. This behavior correlated with chronological age, not with mental age, language development, or parental behavior.…

When two nonhandicapped peers of an autistic five-year old were trained to initiate social interaction, social interaction increased and then dramatically decreased in a reversal phase, and no decrease in the autistic child's disruptive behaviors was observed. When the autistic child was trained to initiate interaction, social interaction…

The maladaptive behaviors, personality, and language skills of a male whose chromosome analysis showed evidence of mosaicism with karyotype 49,XXXXY and 48,XXXY are described. Research on severity of mental handicap with extra chromosomes, delayed speech development, and discrepancy between verbal and performance intelligence is examined. (JDD)

The appropriateness of the Aberrant Behavior Checklist (ABC) was investigated with 199 youngsters with dual diagnosis of mental retardation and psychiatric disturbance. With some cautions, the ABC is recommended, based on the robustness of its factor structure, clinically meaningfulness of the subscale scores, and internal consistency of the…

This commentary discusses study results that indicate the nonselective serotonin reuptake inhibitor (SRI) clomipramine is more efficacious than the relatively selective norepinephrine reuptake inhibitor desipramine and placebo in treating repetitive or ritualized behaviors in children with autism. The need for concurrent genetic and biochemical…

Of a cohort of 104 children with Autism, PDD-NOS or specific language disorder, recruited at age 2-3 years of age, only three appeared to meet diagnostic assessment criteria for Asperger syndrome (AS). The children were followed up at 4-5 years, and assessments at both time points included the Autism Diagnostic Interview (ADI-R), the Autism…

The social skills and problem behaviours of children with high-functioning autism and Asperger's Disorder were compared using parent and teacher reports on the Social Skills Rating System. The participants were 20 children with high-functioning autism, 19 children with Asperger's Disorder, and 17 typically developing children, matched on…

We retrospectively compared 2 groups of children receiving either behavioral treatment (n=13) or eclectic treatment (n=15) for an average of 12 hours per week. Children were assessed on intelligence, language, adaptive functioning and maladaptive behavior at pretreatment and 2 years into treatment. The groups did not differ significantly at…

This study compared behavioral presentation of toddlers with autistic spectrum disorders (ASD) and toddlers with global developmental delay (DD) or developmental language disorder (DLD) who display some characteristics of ASD using the diagnostic algorithm items from the Autism Diagnostic Observation Schedule, Generic (ADOS), the Childhood Autism…

The study demonstrated the effectiveness of a modified Double ABCX or FAAR (Family Adjustment and Adaptation Response) model in predicting successful adaptation (good marital adjustment, few maternal depressive symptoms, and an in-home rating of family functioning) in 45 families of autistic and communication impaired children (ages 2-10).…

In two experiments with profoundly retarded institutionalized individuals, 10 severely aggressive, hyperactive young adults were exposed to two daily periods of jogging and strenuous physical activities. Results indicated systematic reductions in problem behavior for eight of the 10 to levels considered "not a problem" or only "an occasional…

Parents of 42 children (ages 2-32) with Lesch-Nyhan disease were questioned concerning the subjects' behavior patterns. Grouping of responses into nine categories of cognitive skills indicated that only one boy showed any significant cognitive impairment. Despite evidence of good cognitive and emotional skills, subjects were academically delayed,…

Of 135 autistic and/or mentally retarded Tokyo youngsters, 30 with pervasive developmental disorder (PDD) and 2 with nonautistic mental retardation exhibited school refusal. School refusal was significantly more frequent in other PDDs than in nonautistic mental retardation. The intellectual level was significantly higher in PDD children with…