This study investigated demographic and phenomenological characteristics of obsessive compulsive disorder (OCD) in nine adults with Down syndrome (DS), and possible effects on adaptive behavior. Results suggest OCD is more common in the DS population than the non-DS population. Ordering and tidiness was the most common form of OCD found, and…

Explores the problems of definition of sexual behaviors in individuals with autism and describes a case that highlights the difficulties of management. After failure of behavioral and educational programs, a testosterone-suppressing medication was used resulting in suppression of public masturbation behaviors and retention of the participant's…

This commentary discusses the wide acceptance of and the expenditure of limited resources on unproven behavioral therapies for individuals with autism. Considerations that need to be reviewed before adopting a behavioral treatment are outlined, including the need to establish whether direct effects can be attributed to a treatment. (Contains 11…

The possible use of a calendar algorithm was assessed in DBC, an autistic "savant" of normal measured intelligence. Testing of all the dates in a year revealed a random distribution of errors. Re-testing DBC on the same dates one year later shows that his errors were not stable across time. Finally, DBC was able to answer "reversed" questions that…

The study examined cognitive and emotional aspects of development in four infants treated from 10 to 52 months in a reverse isolation environment because of congenital severe combined immunodeficiency disease. Case material is discussed with reference to severe disruption of oral feeding experience, quality of parental involvement, and sensory…

Family systems theory was employed to study sibling relationships in 50 families with a child (ages 4-12) with autism. Typically developing siblings expressed satisfaction with their sibling relationships. Parents were somewhat less positive about the sibling relationships. Stress in the marital relationship was associated with compromised sibling…

Comparison of behavior problems reported by mothers and teachers of 44 children (ages 6 to 15) with Down syndrome and 44 controls without mental retardation indicated that the Down syndrome children had more behavior problems, in particular attention deficit, noncompliance, thought disorder, and social withdrawal. Life events were associated with…

A review of research on the adaptive behavior of persons with both mental retardation and autism/pervasive developmental disorder finds the performances of these dually disabled individuals to be particularly poor in the domain of social skills/socialization and somewhat less poor in the communication domain. In addition, autistic mentally…

A study examined the relationship between neuroimaging findings and the behavioral characteristics of 29 patients with tuberous sclerosis. Findings indicate a positive linear relationship between a patient's total number of tubers and degree of intellectual impairment. The number of tubers in the cerebellum was associated with more autistic…

Results from two studies indicate the nonselective serotonin reuptake inhibitor (SRI) clomipramine is more efficacious than the relatively selective norepinephrine reuptake inhibitor desipramine and placebo in children with autism. A study of the selective SRI fluvoxamine found it to be significantly better than placebo for reducing repetitive…

The "Behavior Problems Inventory" (BPI) is a behavior rating instrument for self-injurious, stereotypic, and aggressive/destructive behavior in mental retardation and other developmental disabilities. Evaluation with 432 residents in a developmental center found the BPI to be a reliable (retest reliability, internal consistency, and…

This article comments on results of a study (EC 629 869) on the reliability of the Modified Checklist for Autism in Toddlers (M-CHAT), a early detection screening test. It discusses concerns relating to clinic vs. population samples, data analysis, use of a parent questionnaire only to identify autism, and the age of screening. (Contains…

This article responds to comments (EC 629 869-70) on a study on the reliability of the Modified Checklist for Autism in Toddlers (M-CHAT), a early detection screening test. It addresses concerns relating to clinic vs. population samples, data analysis, use of a parent questionnaire only to identify autism, and the age of screening. (Contains 6…

There have been few studies of psychopathology in adults with autism. This study examined psychiatric co-morbidity in 147 adults with intellectual disability (ID) and autism and 605 adults with ID but without autism. After controlling for the effects of gender, age, psychotropic medication and level of ID, people with autism and ID were no more…

A review of the empirical research literature on Social Stories[TM] is presented, including a descriptive review and single-subject meta-analysis of appropriate studies. Examination of data suggests the effects of Social Stories[TM] are highly variable. Interpretations of extant studies are frequently confounded by inadequate participant…