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Direct linkYau, Vincent M.; Lutsky, Marta; Yoshida, Cathleen K.; Lasley, Bill; Kharrazi, Martin; Windham, Gayle; Gee, Nancy; Croen, Lisa A. – Journal of Autism and Developmental Disorders, 2015
Thyroid hormones are critical for normal brain development. This study examined autism spectrum disorders (ASD) and thyroid stimulating hormone (TSH) levels measured in mid-pregnancy maternal serum and infant blood after birth. Three groups of children born in Orange County, CA in 2000-2001 were identified: ASD (n = 78), developmental delay…
Descriptors: Metabolism, Autism, Pervasive Developmental Disorders, Pregnancy
Timonen-Soivio, Laura; Sourander, Andre; Malm, Heli; Hinkka-Yli-Salomäki, Susanna; Gissler, Mika; Brown, Alan; Vanhala, Raija – Journal of Autism and Developmental Disorders, 2015
The aim of this study was to evaluate the association between autism spectrum disorders (ASD) with and without intellectual disability (ID) and congenital anomalies (CAs) by organ system. The sample included all children diagnosed with ASD (n = 4441) from the Finnish Hospital Discharge Register during 1987-2000 and a total of four controls per…
Descriptors: Autism, Pervasive Developmental Disorders, Mental Retardation, Children
Schieve, Laura A.; Fountain, Christine; Boulet, Sheree L.; Yeargin-Allsopp, Marshalyn; Kissin, Dmitry M.; Jamieson, Denise J.; Rice, Catherine; Bearman, Peter – Journal of Autism and Developmental Disorders, 2015
Previous studies report associations between conception with assisted reproductive technology (ART) and autism. Whether these associations reflect an ascertainment or biologic effect is undetermined. We assessed diagnosis age and initial autism symptom severity among >30,000 children with autism from a linkage study of California Department of…
Descriptors: Clinical Diagnosis, Age Differences, Autism, Severity (of Disability)
Grether, Judith K.; Qian, Yinge; Croughan, Mary S.; Wu, Yvonne W.; Schembri, Michael; Camarano, Loretta; Croen, Lisa A. – Journal of Autism and Developmental Disorders, 2013
Concerns persist about a possible link between infertility and risk of autism spectrum disorders (ASD). Interpretation of existing studies is limited by racial/ethnic homogeneity of study populations and other factors. Using a case-control design, we evaluated infertility history and treatment documented in medical records of members of Kaiser…
Descriptors: Pregnancy, Autism, Correlation, At Risk Persons
Zerbo, Ousseny; Iosif, Ana-Maria; Walker, Cheryl; Ozonoff, Sally; Hansen, Robin L.; Hertz-Picciotto, Irva – Journal of Autism and Developmental Disorders, 2013
We analyzed data from case groups of 538 children with autism spectrum disorders (ASD) and 163 with developmental delays (DD), and from 421 typically developing controls to assess associations with maternal influenza or fever during pregnancy. Exposure information was obtained by telephone interviews, and outcomes were clinically confirmed. Though…
Descriptors: Pregnancy, Developmental Delays, Genetics, Autism
Whitehouse, Andrew J. O.; Holt, Barbara J.; Serralha, Michael; Holt, Patrick G.; Hart, Prue H.; Kusel, Merci M. H. – Journal of Autism and Developmental Disorders, 2013
We tested whether maternal vitamin D insufficiency during pregnancy is related to the autism phenotype. Serum 25(OH)-vitamin D concentrations of 929 women were measured at 18 weeks' pregnancy. The mothers of the three children with a clinical diagnosis of autism spectrum disorder had 25(OH)-vitamin D concentrations above the population mean.…
Descriptors: Nutrition, Pregnancy, Prenatal Influences, Autism
Xu, Guifeng; Jing, Jin; Bowers, Katherine; Liu, Buyun; Bao, Wei – Journal of Autism and Developmental Disorders, 2014
We performed a systematic literature search regarding maternal diabetes before and during pregnancy and the risk of autism spectrum disorders (ASD) in the offspring. Of the 178 potentially relevant articles, 12 articles including three cohort studies and nine case-control studies were included in the meta-analysis. Both the meta-analyses of cohort…
Descriptors: Diabetes, Pregnancy, At Risk Persons, Literature Reviews
Gidaya, Nicole B.; Lee, Brian K.; Burstyn, Igor; Yudell, Michael; Mortensen, Erik L.; Newschaffer, Craig J. – Journal of Autism and Developmental Disorders, 2014
We investigated whether there is an association between increased risk for autism spectrum disorders (ASD) and selective serotonin reuptake inhibitors (SSRIs) used during pregnancy. This study used Denmark's health and population registers to obtain information regarding prescription drugs, ASD diagnosis, and health and socioeconomic status. There…
Descriptors: Correlation, At Risk Persons, Autism, Pervasive Developmental Disorders
Stoch, Yonit K.; Williams, Cori J.; Granich, Joanna; Hunt, Anna M.; Landau, Lou I.; Newnham, John P.; Whitehouse, Andrew J. O. – Journal of Autism and Developmental Disorders, 2012
An existing randomised controlled trial was used to investigate whether multiple ultrasound scans may be associated with the autism phenotype. From 2,834 single pregnancies, 1,415 were selected at random to receive ultrasound imaging and continuous wave Doppler flow studies at five points throughout pregnancy (Intensive) and 1,419 to receive a…
Descriptors: Pregnancy, Autism, Screening Tests, Symptoms (Individual Disorders)
Visser, Janne C.; Rommelse, Nanda; Vink, Lianne; Schrieken, Margo; Oosterling, Iris J.; Gaag, Rutger J.; Buitelaar, Jan K. – Journal of Autism and Developmental Disorders, 2014
This study examined the differential contribution of pre-and perinatal risks in narrowly versus broadly defined autism spectrum disorder (ASD) and across core symptom domains, IQ and co-morbid problems. Children with a DSM-IV diagnosis of autistic disorder (AD) (n = 121) or pervasive developmental disorder not otherwise specified (PDD-NOS)…
Descriptors: Autism, Pervasive Developmental Disorders, Children, Symptoms (Individual Disorders)
Dodds, Linda; Fell, Deshayne B.; Shea, Sarah; Armson, B. Anthony; Allen, Alexander C.; Bryson, Susan – Journal of Autism and Developmental Disorders, 2011
We conducted a linked database cohort study of infants born between 1990 and 2002 in Nova Scotia, Canada. Diagnoses of autism were identified from administrative databases with relevant diagnostic information to 2005. A factor representing genetic susceptibility was defined as having an affected sibling or a mother with a history of a psychiatric…
Descriptors: Children, Clinical Diagnosis, Autism, Pregnancy
Lee, Brian K.; Gardner, Renee M.; Dal, Henrik; Svensson, Anna; Galanti, Maria Rosaria; Rai, Dheeraj; Dalman, Christina; Magnusson, Cecilia – Journal of Autism and Developmental Disorders, 2012
Prenatal exposure to tobacco smoke is suggested as a potential risk factor for autism spectrum disorders (ASD). Previous epidemiological studies of this topic have yielded mixed findings. We performed a case-control study of 3,958 ASD cases and 38,983 controls nested in a large register-based cohort in Sweden. ASD case status was measured using a…
Descriptors: Smoking, Autism, Pregnancy, Risk
Lampi, Katja M.; Banerjee, P. Nina; Gissler, Mika; Hinkka-Yli-Salomaki, Susanna; Huttunen, Jukka; Kulmala, Ulla; Lindroos, Jarna; Niemela, Solja; Rihko, Maria; Ristkari, Terja; Saanakorpi, Kristiina; Sarlin, Tanja; Sillanmaki, Lauri; McKeague, Ian W.; Surcel, Helja-Marja; Helenius, Hans; Brown, Alan S.; Sourander, Andre – Journal of Autism and Developmental Disorders, 2011
This article presents an overview of the Finnish Prenatal Study of Autism and Autism Spectrum Disorders (FIPS-A), a new study designed to examine the relationship between prenatal serologic factors, mediating and moderating developmental antecedents, and risk of autism spectrum disorders (ASD). The FIPS-A is based on register linkages between…
Descriptors: Autism, Pregnancy, Foreign Countries, Clinics
Whitehouse, Andrew J. O.; Hickey, Martha; Stanley, Fiona J.; Newnham, John P.; Pennell, Craig E. – Journal of Autism and Developmental Disorders, 2011
Fetal head circumference (HC) growth was examined prospectively in children with autism spectrum disorder (ASD). ASD participants (N = 14) were each matched with four control participants (N = 56) on a range of parameters known to influence fetal growth. HC was measured using ultrasonography at approximately 18 weeks gestation and again at birth…
Descriptors: Autism, Pregnancy, Statistical Significance, Human Body
Grether, Judith K.; Li, Sherian Xu; Yoshida, Cathleen K.; Croen, Lisa A. – Journal of Autism and Developmental Disorders, 2010
We evaluated antenatal ultrasound (U/S) exposure as a risk factor for autism spectrum disorders (ASD), comparing affected singleton children and control children born 1995-1999 and enrolled in the Kaiser Permanente health care system. Among children with ASD (n = 362) and controls (n = 393), 13% had no antenatal exposure to U/S examinations;…
Descriptors: Autism, Pregnancy, At Risk Persons, Diagnostic Tests
