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Maternal Mid-Gestation Cytokine Dysregulation in Mothers of Children with Autism Spectrum Disorder
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Casey, S.; Carter, M.; Looney, A. M.; Livingstone, V.; Moloney, G.; O'Keeffe, G. W.; Taylor, R. S.; Kenny, L. C.; McCarthy, F. P.; McCowan, L. M. E.; Thompson, J. M. D.; Murray, D. M. – Journal of Autism and Developmental Disorders, 2022
Autism spectrum disorder (ASD) is a developmental disorder characterised by deficits in social interactions and communication, with stereotypical and repetitive behaviours. Recent evidence suggests that maternal immune dysregulation may predispose offspring to ASD. Independent samples t-tests revealed downregulation of IL-17A concentrations in…
Descriptors: Mothers, Children, Autism, Pervasive Developmental Disorders
Peri-Pregnancy Cannabis Use and Autism Spectrum Disorder in the Offspring: Findings from the Study to Explore Early Development
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DiGuiseppi, Carolyn; Crume, Tessa; Van Dyke, Julia; Sabourin, Katherine R.; Soke, Gnakub N.; Croen, Lisa A.; Daniels, Julie L.; Lee, Li-Ching; Schieve, Laura A.; Windham, Gayle C.; Friedman, Sandra; Robinson Rosenberg, Cordelia – Journal of Autism and Developmental Disorders, 2022
The association of autism spectrum disorder (ASD) with self-reported maternal cannabis use from 3 months pre-conception to delivery ("peri-pregnancy") was assessed in children aged 30-68 months, born 2003 to 2011. Children with ASD (N = 1428) were compared to children with other developmental delays/disorders (DD, N = 1198) and…
Descriptors: Pregnancy, Prenatal Influences, Marijuana, Drug Use
Brief Report: Maternal Opioid Prescription from Preconception through Pregnancy and the Odds of Autism Spectrum Disorder and Autism Features in Children
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Rubenstein, Eric; Young, Jessica C.; Croen, Lisa A.; DiGuiseppi, Carolyn; Dowling, Nicole F.; Lee, Li-Ching; Schieve, Laura; Wiggins, Lisa D.; Daniels, Julie – Journal of Autism and Developmental Disorders, 2019
Opioid use during pregnancy is associated with suboptimal pregnancy outcomes. Little is known about child neurodevelopmental outcomes. We examined associations between maternal opioid prescriptions preconception to delivery (peri-pregnancy) and child's risk of ASD, developmental delay/disorder (DD) with no ASD features, or ASD/DD with autism…
Descriptors: Mothers, Narcotics, Autism, Pervasive Developmental Disorders
Prenatal and Neonatal Thyroid Stimulating Hormone Levels and Autism Spectrum Disorders
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Yau, Vincent M.; Lutsky, Marta; Yoshida, Cathleen K.; Lasley, Bill; Kharrazi, Martin; Windham, Gayle; Gee, Nancy; Croen, Lisa A. – Journal of Autism and Developmental Disorders, 2015
Thyroid hormones are critical for normal brain development. This study examined autism spectrum disorders (ASD) and thyroid stimulating hormone (TSH) levels measured in mid-pregnancy maternal serum and infant blood after birth. Three groups of children born in Orange County, CA in 2000-2001 were identified: ASD (n = 78), developmental delay…
Descriptors: Metabolism, Autism, Pervasive Developmental Disorders, Pregnancy
Prenatal Stress and Risk of Febrile Seizures in Children: A Nationwide Longitudinal Study in Denmark
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Li, Jiong; Olsen, Jorn; Obel, Carsten; Christensen, Jakob; Precht, Dorthe Hansen; Vestergaard, Mogens – Journal of Autism and Developmental Disorders, 2009
We aimed to examine whether exposure to prenatal stress following maternal bereavement is associated with an increased risk of febrile seizures. In a longitudinal population-based cohort study, we followed 1,431,175 children born in Denmark. A total of 34,777 children were born to women who lost a close relative during pregnancy or within 1 year…
Descriptors: Grief, Seizures, Pregnancy, Foreign Countries
A Prospective Case Report of Infantile Autism from Pregnancy to Four Years.
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Sparling, Joyce W. – Journal of Autism and Developmental Disorders, 1991
This case study provides early developmental data about a child later diagnosed as autistic. The report describes results of serial ultrasounds performed during the pregnancy, the complication of maternal diabetes, family history, high maternal stress levels, avoidance behaviors of the infant, and developmental delays exhibited especially in…
Descriptors: Autism, Case Studies, Child Development, Developmental Stages