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Direct linkScheithauer, Mindy; Call, Nathan A.; Lomas Mevers, Joanna; McCracken, Courtney E.; Scahill, Lawrence – Journal of Autism and Developmental Disorders, 2021
Elopement is a common and dangerous concern in autism spectrum disorder (ASD). There is evidence that behavior analytic treatments can successfully treat elopement, but the research is limited due to small samples and treatment components varying across studies. The current study evaluated the feasibility of studying a manualized intervention for…
Descriptors: Randomized Controlled Trials, Intervention, Behavior Problems, Children
Chez, Michael; Kile, Shawn; Lepage, Christopher; Parise, Carol; Benabides, Bobbie; Hankins, Andrea – Journal of Autism and Developmental Disorders, 2020
Prior studies have demonstrated successful irritability treatment using dopaminergic antagonists in autistic patients. The purpose of this pilot study was to assess the effect of dextromethorphan/quinidine (DM/Q) in autistic adults (18-60 years of age). This was a randomized, blinded, crossover, study of 14 patients randomized to DM/Q or a placebo…
Descriptors: Outcomes of Treatment, Randomized Controlled Trials, Pilot Projects, Drug Therapy
Wink, Logan K.; Adams, Ryan; Horn, Paul S.; Tessier, Charles R.; Bantel, Andrew P.; Hong, Michael; Shaffer, Rebecca C.; Pedapati, Ernest V.; Erickson, Craig A. – Journal of Autism and Developmental Disorders, 2018
Riluzole is a glutamatergic modulator of particular interest in autism spectrum disorder (ASD). In this 12-week randomized, double-blind, placebo-controlled, crossover pilot study we evaluated the safety and tolerability of 5-week of adjunctive riluzole treatment (vs. 5-week of placebo, with 2-week washout period) targeting ASD-associated…
Descriptors: Drug Therapy, Autism, Pervasive Developmental Disorders, Safety
