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Flowers, Jacqueline; Lantz, Johanna; Hamlin, Terry; Simeonsson, Rune J. – Journal of Autism and Developmental Disorders, 2020
Self-injurious behavior (SIB) occurs in up to 50% of individuals with autism. As one of the most serious conditions in individuals with developmental disabilities, SIB affects the individual and his or her family in multiple contexts. A systematic analysis of factors most commonly associated with SIB could inform the development of individualized…
Descriptors: Self Destructive Behavior, Injuries, Autism, Pervasive Developmental Disorders
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Eckert, Eleanor M.; Dominick, Kelli C.; Pedapati, Ernest V.; Wink, Logan K.; Shaffer, Rebecca C.; Andrews, Howard; Choo, Tse-Hwei; Chen, Chen; Kaufmann, Walter E.; Tartaglia, Nicole; Berry-Kravis, Elizabeth M.; Erickson, Craig A. – Journal of Autism and Developmental Disorders, 2019
Using a dataset involving 415 individuals with irritability, aggression, agitation and self-injury (IAAS) behaviors from the fragile X syndrome (FXS) FORWARD database, we describe the psychopharmacologic management of IAAS and features of the population of persons with FXS treated with drug therapy for IAAS. Among those with FXS exhibiting IAAS,…
Descriptors: Genetic Disorders, Self Destructive Behavior, Aggression, Behavior Problems
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Crawford, Hayley; Karakatsani, Efthalia; Singla, Gursharan; Oliver, Chris – Journal of Autism and Developmental Disorders, 2019
Self-injurious and aggressive behaviors are common in fragile X syndrome (FXS). However, little is known about the persistence of these behaviors and associated risk markers. We established the prevalence and persistence of self-injurious and aggressive behaviors over eight years in males with FXS, and associations with risk markers. Results…
Descriptors: Self Destructive Behavior, Aggression, Males, Genetic Disorders
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Nicotera, Antonio Gennaro; Hagerman, Randi Jenssen; Catania, Maria Vincenza; Buono, Serafino; Di Nuovo, Santo; Liprino, Elisa Maria; Stracuzzi, Emanuela; Giusto, Stefania; Di Vita, Giuseppina; Musumeci, Sebastiano Antonino – Journal of Autism and Developmental Disorders, 2019
To date, the phenotypic significance of EEG abnormalities in patients with ASD is unclear. In a population affected by ASD we aimed to evaluate: the phenotypic characteristics; the prevalence of EEG abnormalities; the potential correlations between EEG abnormalities and behavioral and cognitive variables. Sixty-nine patients with ASD underwent…
Descriptors: Autism, Pervasive Developmental Disorders, Neurological Impairments, Diagnostic Tests
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Santiago, Joana L.; Hanley, Gregory P.; Moore, Keira; Jin, C. Sandy – Journal of Autism and Developmental Disorders, 2016
Behavioral interventions preceded by a functional analysis have been proven efficacious in treating severe problem behavior associated with autism. There is, however, a lack of research showing socially validated outcomes when assessment and treatment procedures are conducted by ecologically relevant individuals in typical settings. In this study,…
Descriptors: Intervention, Self Destructive Behavior, Aggression, Interpersonal Competence
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Oliver, Chris; Petty, Jane; Ruddick, Loraine; Bacarese-Hamilton, Monique – Journal of Autism and Developmental Disorders, 2012
We evaluated the independent association between adaptive behavior, communication and repetitive or ritualistic behaviors and self-injury, aggression and destructive behavior to identify potential early risk markers for challenging behaviors. Data were collected for 943 children (4-18 years, M = 10.88) with severe intellectual disabilities. Odds…
Descriptors: Aggression, Severe Mental Retardation, Injuries, Behavior Problems
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Maskey, Morag; Warnell, Frances; Parr, Jeremy R.; Le Couteur, Ann; McConachie, Helen – Journal of Autism and Developmental Disorders, 2013
The type, frequency and inter-relationships of emotional and behavioural problems in 863 children with autism spectrum disorder (ASD) were investigated using the population-based Database of children with ASD living in the North East of England (Daslne). A high rate of problems was reported, with 53% of children having 4 or more types of problems…
Descriptors: Autism, Foreign Countries, Pervasive Developmental Disorders, Emotional Disturbances
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Cohen, Ira L.; Tsiouris, John A.; Flory, Michael J.; Kim, Soh-Yule; Freedland, Robert; Heaney, Glenn; Pettinger, Jill; Brown, W. Ted – Journal of Autism and Developmental Disorders, 2010
The psychometric characteristics of the IBR Modified Overt Aggression Scale were studied in over 2,000 people with Intellectual Disability (ID). Reliability ranged from good to excellent. Aggression toward others and objects was highest in the youngest adults, in those in the moderate to severe range of ID, and in those with an autism spectrum…
Descriptors: Aggression, Females, Mental Retardation, Autism
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Hessl, David; Tassone, Flora; Cordeiro, Lisa; Koldewyn, Kami; McCormick, Carolyn; Green, Cherie; Wegelin, Jacob; Yuhas, Jennifer; Hagerman, Randi J. – Journal of Autism and Developmental Disorders, 2008
Although fragile X syndrome (FXS) is a single gene disorder with a well-described phenotype, it is not known why some individuals develop more significant maladaptive behaviors such as aggression or autistic symptoms. Here, we studied two candidate genes known to affect mood and aggression, the serotonin transporter (5-HTTLPR) and monoamine…
Descriptors: Autism, Etiology, Males, Aggression
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Scahill, Lawrence; Aman, Michael G.; McDougle, Christopher J.; Arnold, L. Eugene; McCracken, James T.; Handen, Benjamin; Johnson, Cynthia; Dziura, James; Butter, Eric; Sukhodolsky, Denis; Swiezy, Naomi; Mulick, James; Stigler, Kimberly; Bearss, Karen; Ritz, Louise; Wagner, Ann; Vitiello, Benedetto – Journal of Autism and Developmental Disorders, 2009
This paper presents the rationale for a 24-week, randomized trial designed to test whether risperidone plus structured parent training would be superior to risperidone only on measures of noncompliance, irritability and adaptive functioning. In this model, medication reduces tantrums, aggression and self-injury; parent training promotes…
Descriptors: Intervention, Pervasive Developmental Disorders, Parent Education, Drug Therapy
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Mandell, David S. – Journal of Autism and Developmental Disorders, 2008
This study examined predictors of psychiatric hospitalization among children with autism spectrum disorders (ASD). Data were collected from 760 caregivers of children with ASD. Cox regression was used to determine factors associated with hospitalization. Almost 11% were hospitalized. Youth in single parent homes were more likely to be hospitalized…
Descriptors: Hospitalized Children, Pervasive Developmental Disorders, At Risk Persons, Correlation