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Profiles of Social and Coping Resources in Families of Children with Autism Spectrum Disorder: Relations to Parent and Child Outcomes
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Zaidman-Zait, Anat; Mirenda, Pat; Szatmari, Peter; Duku, Eric; Smith, Isabel M.; Vaillancourt, Tracy; Volden, Joanne; Waddell, Charlotte; Bennett, Teresa; Zwaigenbaum, Lonnie; Elsabaggh, Mayada; Georgiades, Stelios – Journal of Autism and Developmental Disorders, 2018
This study described empirically derived profiles of parents' personal and social coping resources in a sample of 207 families of children diagnosed with autism spectrum disorder. Latent Profile Analysis identified four family profiles based on socieoeconomic risk, coping strategy utilization, family functioning, available social supports, and…
Descriptors: Coping, Pervasive Developmental Disorders, Autism, Behavior Problems
DNA Methylation of the Oxytocin Receptor across Neurodevelopmental Disorders
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Siu, Michelle T.; Goodman, Sarah J.; Yellan, Isaac; Butcher, Darci T.; Jangjoo, Maryam; Grafodatskaya, Daria; Rajendram, Rageen; Lou, Youliang; Zhang, Rujun; Zhao, Chunhua; Nicolson, Rob; Georgiades, Stelios; Szatmari, Peter; Scherer, Stephen W.; Roberts, Wendy; Anagnostou, Evdokia; Weksberg, Rosanna – Journal of Autism and Developmental Disorders, 2021
Many neurodevelopmental disorders (NDDs) share common learning and behavioural impairments, as well as features such as dysregulation of the oxytocin hormone. Here, we examined DNA methylation (DNAm) in the 1st intron of the oxytocin receptor gene, "OXTR," in patients with autism spectrum (ASD), attention deficit and hyperactivity (ADHD)…
Descriptors: Genetics, Autism, Pervasive Developmental Disorders, Biochemistry
Relationship between Early Social-Emotional Behavior and Autism Spectrum Disorder: A High-Risk Sibling Study
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Raza, Sarah; Sacrey, Lori-Ann R.; Zwaigenbaum, Lonnie; Bryson, Susan; Brian, Jessica; Smith, Isabel M.; Roberts, Wendy; Szatmari, Peter; Vaillancourt, Tracy; Roncadin, Caroline; Garon, Nancy – Journal of Autism and Developmental Disorders, 2020
Social-emotional behavior in autism spectrum disorder (ASD) was examined among high-risk (HR; siblings of children diagnosed with ASD) and low-risk (LR; no family history of ASD) toddlers. Caregivers completed the Infant-Toddler Social Emotional Assessment (ITSEA) at 18 months, and blind diagnostic assessment for ASD was conducted at 36 months.…
Descriptors: Autism, Pervasive Developmental Disorders, Genetics, Clinical Diagnosis
Examination of Bidirectional Relationships between Parent Stress and Two Types of Problem Behavior in Children with Autism Spectrum Disorder
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Zaidman-Zait, Anat; Mirenda, Pat; Duku, Eric; Szatmari, Peter; Georgiades, Stelios; Volden, Joanne; Zwaigenbaum, Lonnie; Vaillancourt, Tracy; Bryson, Susan; Smith, Isabel; Fombonne, Eric; Roberts, Wendy; Waddell, Charlotte; Thompson, Ann – Journal of Autism and Developmental Disorders, 2014
Path analysis within a structural equation modeling framework was employed to examine the relationships between two types of parent stress and children's externalizing and internalizing behaviors over a 4-year period, in a sample of 184 mothers of young children with autism spectrum disorder. Parent stress was measured with the Parenting Stress…
Descriptors: Path Analysis, Structural Equation Models, Stress Variables, Child Rearing
Phenotypic Overlap between Core Diagnostic Features and Emotional/Behavioral Problems in Preschool Children with Autism Spectrum Disorder
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Georgiades, Stelios; Szatmari, Peter; Duku, Eric; Zwaigenbaum, Lonnie; Bryson, Susan; Roberts, Wendy; Fombonne, Eric; Mirenda, Pat; Smith, Isabel; Vaillancourt, Tracy; Volden, Joanne; Waddell, Charlotte; Thompson, Ann – Journal of Autism and Developmental Disorders, 2011
This study examined the phenotypic overlap between core diagnostic features and emotional/behavioral problems in a sample of 335 preschool children with autism spectrum disorder (ASD). Results from principal component analysis (2 components; 49.70% variance explained) suggested substantial phenotypic overlap between core diagnostic features and…
Descriptors: Autism, Preschool Children, Pervasive Developmental Disorders, Behavior Problems
Validating the Repetitive Behavior Scale-Revised in Young Children with Autism Spectrum Disorder
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Mirenda, Pat; Smith, Isabel M.; Vaillancourt, Tracy; Georgiades, Stelios; Duku, Eric; Szatmari, Peter; Bryson, Susan; Fombonne, Eric; Roberts, Wendy; Volden, Joanne; Waddell, Charlotte; Zwaigenbaum, Lonnie – Journal of Autism and Developmental Disorders, 2010
This study examined the factor structure of the Repetitive Behavior Scale-Revised (RBS-R) in a sample of 287 preschool-aged children with autism spectrum disorder (ASD). A confirmatory factor analysis was used to examine six competing structural models. Spearman's rank order correlations were calculated to examine the associations between factor…
Descriptors: Check Lists, Autism, Factor Structure, Young Children
A Chart Review of Schizotypal Personality Disorders in Children.
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Nagy, Joan; Szatmari, Peter – Journal of Autism and Developmental Disorders, 1986
The literature on the diagnostic validity of schizotypal personality disorders (SPD) in childhood is reviewed, and the results of a chart review of 20 SPD children meeting Diagnostic and Statistical Manual III criteria are presented suggesting that SPD in childhood exists and warrants study. (Author/CB)
Descriptors: Adolescents, Children, Clinical Diagnosis, Diagnostic Tests