Background: People with intellectual disabilities may experience frailty earlier than the general population. This scoping review aimed to investigate how frailty is defined, assessed, and managed in adults with an intellectual disability; factors associated with frailty; and the potential impact of COVID-19 on frailty identification and…

Background: Views can be collected from individuals (self-report) or others on their behalf (proxy-report). Objective: We aimed to review the literature on methods and statistical approaches used to evaluate observer versus self-report responses from individuals with intellectual disability or Down syndrome. Methods: A series of key questions…

Background: Adults with intellectual disability, especially those with Down syndrome, are at increased risk of dementia. Whilst memory decline is often considered the earliest symptom, emerging research indicates decline in language, executive function, and non-cognitive domains may also occur early, potentially before memory changes. Method: A…

Background: Individuals with Down syndrome (DS) experience health disparities possibly associated with high levels of sedentary behaviour (SB). We systematically reviewed SB measurement, levels, patterns, correlates, consequences and interventions in people with DS across the lifespan. Method: We searched these databases: Embase; PubMed; Web of…