The mastery of vocabulary is a fundamental step when learning a language but for many learners, it seems difficult and boring. English as Foreign Language (EFL) learners find some difficulties in learning new words. The aim of this study was to examine the effect of using the hologram application in learning medical English terminology for EFL learners. The study involved 109 EFL learners studying at a medical college to determine if a holographic tool affected their learning. They were divided into three groups: a control group using traditional methods to learn new medical terms (no technology was used), and two experimental groups. One experimental group was taught using PowerPoint without the holographic application, while the other experimental group was taught using the holographic application. The data were collected using the pre-, post-, and delayed post-test design. The findings of the study indicated that learners who were taught using the holographic application outscored other groups and remembered more medical English terms after three weeks. Moreover, the learners felt the hologram application had a positive impact on learning medical terms.