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Andrija Babic; Ognjen Barcot; Tomislav Viskovic; Frano Šaric; Aleksandar Kirkovski; Ivana Barun; Zvonimir Križanac; Roshan Arjun Ananda; Yuli Viviana Fuentes Barreiro; Narges Malih; Daiana Anne-Marie Dimcea; Josipa Ordulj; Ishanka Weerasekara; Matteo Spezia; Marija Franka Žuljevic; Jelena Šuto; Luca Tancredi; Andela Pijuk; Susanna Sammali; Veronica Iascone; Thilo Groote; Tina Poklepovic Pericic; Livia Puljak – Research Synthesis Methods, 2024
Risk of bias (RoB) assessment is essential to the systematic review methodology. The new version of the Cochrane RoB tool for randomized trials (RoB 2) was published in 2019 to address limitations identified since the first version of the tool was published in 2008 and to increase the reliability of assessments. This study analyzed the frequency…
Descriptors: Risk, Bias, Use Studies, Meta Analysis
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Timo Gnambs; Ulrich Schroeders – Research Synthesis Methods, 2024
Meta-analyses of treatment effects in randomized control trials are often faced with the problem of missing information required to calculate effect sizes and their sampling variances. Particularly, correlations between pre- and posttest scores are frequently not available. As an ad-hoc solution, researchers impute a constant value for the missing…
Descriptors: Accuracy, Meta Analysis, Randomized Controlled Trials, Effect Size
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Nejstgaard, Camilla Hansen; Laursen, David Ruben Teindl; Lundh, Andreas; Hróbjartsson, Asbjørn – Research Synthesis Methods, 2023
We investigated to which degree commercial funding is associated with estimated intervention effects in randomized trials. We included meta-epidemiological studies with published data on the association between commercial funding and results or conclusions of randomized trials. We searched five databases and other sources. We selected one result…
Descriptors: Private Financial Support, Intervention, Randomized Controlled Trials, Literature Reviews
Emma R. Hart; Drew H. Bailey; Sha Luo; Pritha Sengupta; Tyler W. Watts – Annenberg Institute for School Reform at Brown University, 2024
Researchers and policymakers aspire for educational interventions to change children's long-run developmental trajectories. However, intervention impacts on cognitive and achievement measures commonly fade over time. Less is known, although much is theorized, about social-emotional skill persistence. The current meta-analysis investigated whether…
Descriptors: Literature Reviews, Meta Analysis, Children, Adolescents
Mindy L. Rosengarten; Emma R. Hart; Drew H. Bailey; Meghan P. McCormick; Benjamin J. Lovett; Tyler W. Watts – Annenberg Institute for School Reform at Brown University, 2024
Recent reviews of the educational intervention literature have noted patterns of intervention impact fadeout on cognitive skills, whereby skill trajectories between children in the intervention and control group converge in the years following the end of the intervention. Some early childhood education (ECE) researchers have suggested that skill…
Descriptors: Data Analysis, Meta Analysis, Intervention, Persistence
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Rrita Zejnullahi – Society for Research on Educational Effectiveness, 2021
Background: Meta-analysis is considered to be the gold standard for evidence synthesis. It involves combining data from multiple independent sources to produce a summary estimate with improved precision. Traditionally, meta-analysis methods have been applied to a large collection of studies, and past research efforts have indicated its numerous…
Descriptors: Meta Analysis, Randomized Controlled Trials, Sample Size, Best Practices
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Yao, Minghong; Wang, Yuning; Ren, Yan; Jia, Yulong; Zou, Kang; Li, Ling; Sun, Xin – Research Synthesis Methods, 2023
Rare events meta-analyses of randomized controlled trials (RCTs) are often underpowered because the outcomes are infrequent. Real-world evidence (RWE) from non-randomized studies may provide valuable complementary evidence about the effects of rare events, and there is growing interest in including such evidence in the decision-making process.…
Descriptors: Evidence, Meta Analysis, Randomized Controlled Trials, Decision Making
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Deborah M. Caldwell; Jennifer C. Palmer; Katie E. Webster; Sarah R. Davies; Hugo Hughes; Joseph Rona; Rachel Churchill; Sarah E. Hetrick; Nicky J. Welton – Prevention Science, 2025
Many randomized controlled trials have investigated the role of school-based prevention interventions to reduce symptoms of anxiety and depression in young people. Systematic reviews have subsequently demonstrated a small, beneficial effect of these interventions when compared to a combined control group including usual care, no intervention, or…
Descriptors: Depression (Psychology), Prevention, Randomized Controlled Trials, Symptoms (Individual Disorders)
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Edoardo G. Ostinelli; Orestis Efthimiou; Yan Luo; Clara Miguel; Eirini Karyotaki; Pim Cuijpers; Toshi A. Furukawa; Georgia Salanti; Andrea Cipriani – Research Synthesis Methods, 2024
When studies use different scales to measure continuous outcomes, standardised mean differences (SMD) are required to meta-analyse the data. However, outcomes are often reported as endpoint or change from baseline scores. Combining corresponding SMDs can be problematic and available guidance advises against this practice. We aimed to examine the…
Descriptors: Network Analysis, Meta Analysis, Depression (Psychology), Regression (Statistics)
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McDaniel, Jena; Brady, Nancy C.; Warren, Steven F. – Journal of Autism and Developmental Disorders, 2022
We conducted a systematic review to identify randomized controlled trials (RCTs) and single case research design (SCRD) studies of children with autism spectrum disorder that evaluate the effectiveness of responsivity intervention techniques for improving prelinguistic and/or language outcomes. Mean effect sizes were moderate and large for RCTs…
Descriptors: Outcomes of Treatment, Response to Intervention, Child Language, Autism Spectrum Disorders
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Proctor, Tanja; Zimmermann, Samuel; Seide, Svenja; Kieser, Meinhard – Research Synthesis Methods, 2022
During drug development, a biomarker is sometimes identified as separating a patient population into those with more and those with less benefit from evaluated treatments. Consequently, later studies might be targeted, while earlier ones are performed in mixed patient populations. This poses a challenge in evidence synthesis, especially if only…
Descriptors: Comparative Analysis, Meta Analysis, Patients, Medical Research
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Held, Leonhard; Matthews, Robert; Ott, Manuela; Pawel, Samuel – Research Synthesis Methods, 2022
It is now widely accepted that the standard inferential toolkit used by the scientific research community--null-hypothesis significance testing (NHST)--is not fit for purpose. Yet despite the threat posed to the scientific enterprise, there is no agreement concerning alternative approaches for evidence assessment. This lack of consensus reflects…
Descriptors: Bayesian Statistics, Statistical Inference, Hypothesis Testing, Credibility
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Cope, Shannon; Chan, Keith; Jansen, Jeroen P. – Research Synthesis Methods, 2020
Background: Network meta-analysis (NMA) of survival data with a multidimensional treatment effect has been introduced as an alternative to NMA based on the proportional hazards assumption. However, these flexible models have some limitations, such as the use of an approximate likelihood based on discrete hazards, rather than a likelihood for…
Descriptors: Multivariate Analysis, Meta Analysis, Network Analysis, Models
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Sini Li; Yijing Yong; Yamin Li; Jianhe Li; Jiao Xie – Journal of Autism and Developmental Disorders, 2024
This review aims to systematically summarize existing evidence to determine the effectiveness of cognitive-based interventions (CBIs) on psychological health and well-being among parents of children with developmental disabilities (DD). Six databases were searched to identify eligible randomized controlled trials (RCTs) from their inception to…
Descriptors: Parents, Children, Developmental Disabilities, Metacognition
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Churches, Richard; Dommett, Eleanor J.; Devonshire, Ian M.; Hall, Robin; Higgins, Steve; Korin, Astrid – Mind, Brain, and Education, 2020
We initiated and structured a single program that supervised teachers, some with neuroscience or psychology degrees, to collaborate and explore the effects of science of learning-translated pedagogy. This article reports on the 34 findings from teacher-led randomized controlled trials (RCTs) and replications. Teachers designed trials, looking at…
Descriptors: Randomized Controlled Trials, Teacher Researchers, Research Design, Attention
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