Associative learning abilities vary considerably among individuals, with attentional processes suggested to play a role in these variations. However, the relationship between attentional processes and individual differences in associative learning remains unclear, and whether these variations reflect in event-related potentials (ERPs) is unknown.…

Visual objects are often defined by multiple features. Therefore, learning novel objects entails learning feature conjunctions. Visual cortex is organized into distinct anatomical compartments, each of which is devoted to processing a single feature. A prime example are neurons purely selective to color and orientation, respectively. However,…

This study investigated whether transcranial direct current stimulation (tDCS) targeting the inferior frontal gyrus (IFG) can alter the thinking process and neural basis of creativity. Participants' performance on the compound remote associates (CRA) task was analyzed considering the semantic features of each trial after receiving different tDCS…

Key areas of the episodic memory (EM) network demonstrate changing structure and volume during adolescence. EM is multifaceted and yet studies of EM thus far have largely examined single components, used different methods and have unsurprisingly yielded inconsistent results. The Treasure Hunt task is a single paradigm that allows parallel…

Chance favors the prepared mind, said Louis Pasteur. Sometimes, significant breakthroughs occur when we creatively integrate new information, leading to a creative insight or an Aha! moment, while at other times when we fail to use a clue, we remain stuck in our habitual thinking patterns. In this study, we hypothesized that the brain's transient…

Temporal association learning (TAL) allows for the linkage of distinct, nonsynchronous events across a period of time. This function is driven by neural interactions in the entorhinal cortical-hippocampal network, especially the neural input from the pyramidal cells in layer III of medial entorhinal cortex (MECIII) to hippocampal CA1 is crucial…

Associative thinking plays a major role in creativity, as it involves the ability to link distant concepts. Yet, the neural mechanisms allowing to combine distant associates in creative thinking tasks remain poorly understood. We investigated the whole-brain functional connectivity patterns related to combining remote associations for creative…

In many domains, learners extract recurring units from continuous sequences. For example, in unknown languages, fluent speech is perceived as a continuous signal. Learners need to extract the underlying words from this continuous signal and then memorize them. One prominent candidate mechanism is statistical learning, whereby learners track how…

Creativity is a fundamental human accomplishment from scientific advances to composing music. The left dorsolateral prefrontal cortex (DLPFC) and inferior frontal gyrus (IFG) are important metacontrol hubs in flexibility and persistence brain states, respectively. Those hubs are related to divergent thinking, insight problem-solving, and…

During the first ten postnatal days (P), infant rodents can learn olfactory preferences for novel odors if they are paired with thermo-tactile stimuli that mimic components of maternal care. After P10, the thermo-tactile pairing becomes ineffective for conditioning. The current explanation for this change in associative learning is the alteration…

The basolateral amygdala (BLA) is a temporal lobe structure that contributes to a host of behaviors. In particular, it is a central player in learning about aversive events and thus assigning emotional valence to sensory events. It is a cortical-like structure and contains glutamatergic pyramidal neurons and GABAergic interneurons. It is divided…

Remote association, the ability to form new relations between independent elements, was assessed using the Remote Associates Test (RAT). The Chinese RAT (CRAT) includes the Chinese radical RAT (CRRAT), Chinese word RAT (CWRAT), and Chinese compound RAT (CCRAT). Behavioral research indicates that an individual's performance on the CRAT reflects…

Successful episodic memory requires binding of event details across spatial and temporal gaps. The neural processes underlying mnemonic binding, however, are not fully understood. Moreover, although acute stress is known to modulate memory, if and how stress changes mnemonic integration across time and space is unknown. To elucidate these issues,…

Impaired abilities in multiple domains is common in children with learning difficulties. Co-occurrence of low reading and mathematical abilities (LRLM) appears in almost every second child with learning difficulties. However, little is known regarding the neural bases of this combination. Leveraging a unique and tightly controlled sample including…

Few studies have compared interference-based forgetting between item versus associative memory. The memory-system dependent forgetting hypothesis (Hardt, Nader, & Nadel, 2013) predicts that effects of interference on associative memory should be minimal because its hippocampal representation allows pattern separation even of highly similar…