Full-term infants who had slept in the prone position since birth were followed to detect early postural abnormalities and differentiate potential peripheral abnormality from abnormalities of a central origin. Results showed that disappearance of initial signs of abnormality appeared to be muscular, and symptoms disappeared faster when a motor…

This study of eight growth-retarded children with Down's syndrome (aged 1 to 6.5 years) found that administration of growth hormone was more effective than either L-dopa or clonidine. Results suggest that children with Down's syndrome have both anatomical and biochemical hypothalamic derangements resulting in decreased growth hormone secretion and…

Morphometric analysis of magnetic resonance imaging scans revealed that, compared to nondisabled controls, the seven children with attention deficit hyperactivity disorder had a smaller corpus callosum. Results suggest that subtle differences may exist in the brains of these children and that deviations in normal corticogenesis may underlie the…

Three self-report methods for rating secondary sexual characteristic growth were compared to physician ratings; the accuracy of self-reported height and weight was also assessed. The usefulness of the Pubertal Development Scale, Tanner ratings, and self-reported height and weight as adequate estimates of pubertal development is discussed. (PCB)

Comparison of growth rates and menarcheal age for groups of boys and girls, ages 6 to 15, in Tokyo (Japan) found that children with mental retardation had a smaller growth spurt during puberty but did not differ in maturational rate defined by age at pubertal height spurt or age at menarche. (Author/DB)

Examines the impact of pubertal status and timing, independent of chronological age, on the family relationships of adolescents in 204 families with a firstborn child between the ages of 10 and 15. Measures included adolescent and parental reports of closeness, confict, and autonomy and assessments of adolesents' pubertal status and pubertal…

Studied the sleep state organization and EEG patterns at term date in 53 preterm infants as an index of the maturity and integrity of neurophysiological organization that may have implications for their later development. (HOD)

The isokinetic strength of the knee extensor muscles of both limbs was evaluated in 25 children and adolescents with Down's syndrome. The Down's syndrome subjects were significantly weaker than control groups with average intelligence and with non-Down's syndrome mental retardation. Results suggested a dysfunction of the neuromuscular system,…

Children diagnosed with environmentally based failure to thrive early during their first year of life were seen at 12 and 18 months for assessment of psychological development (cognition, language, symbolic play, and behavior during testing). Based on a transactional model of outcome, factors reflecting biological vulnerability (wasting and…