Our system of research self-regulation, designed to provide internal checks and balances for those who participate in research involving human subjects, is under considerable stress. Much of this crisis has been caused by what we call mission creep, in which the workload of IRBs has expanded beyond their ability to handle effectively. Mission…

Academic freedom and the protection of human research subjects are central tenets of American universities. Academic freedom protects the rights of tenured professors to conduct autonomous research; human subject protection ensures that research causes as minimal a risk as possible to study participants. Although the two principles are mutually…