The neurobiology of borderline personality disorder (BPD) remains unclear. Dysfunctions of several neurobiological systems, including serotoninergic, dopaminergic, and other neurotransmitter systems, have been discussed. Here we present a theory that alterations in the sensitivity of opioid receptors or the availability of endogenous opioids…

Over the past several decades, research has focused increasingly on developmental precursors to psychological disorders that were previously assumed to emerge only in adulthood. This change in focus follows from the recognition that complex transactions between biological vulnerabilities and psychosocial risk factors shape emotional and behavioral…

A case study is presented of a male adolescent whose behavior became increasingly rebellious, rejecting, antisocial, and self-destructive. His family's unsuccessful attempts to resolve the problems are described from the point of view of the counselor, followed by suggestions for building character and coping with changes during adolescence. (JDD)