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Godolphin, Peter J.; White, Ian R.; Tierney, Jayne F.; Fisher, David J. – Research Synthesis Methods, 2023
Estimation of within-trial interactions in meta-analysis is crucial for reliable assessment of how treatment effects vary across participant subgroups. However, current methods have various limitations. Patients, clinicians and policy-makers need reliable estimates of treatment effects within specific covariate subgroups, on relative and absolute…
Descriptors: Meta Analysis, Outcomes of Treatment, Medical Research, Comparative Analysis