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Direct linkCairns, Maxwell; Prendergast, Luke A. – Research Synthesis Methods, 2022
As a measure of heterogeneity in meta-analysis, the coefficient of variation (CV) has been recently considered, providing researchers with a complement to the very popular I[superscript 2] measure. While I[superscript 2] measures the proportion of total variance that is due to variance of the random effects, the CV is the ratio of the standard…
Descriptors: Meta Analysis, Statistical Analysis, Intervals, Computation
Noma, Hisashi; Hamura, Yasuyuki; Gosho, Masahiko; Furukawa, Toshi A. – Research Synthesis Methods, 2023
Network meta-analysis has been an essential methodology of systematic reviews for comparative effectiveness research. The restricted maximum likelihood (REML) method is one of the current standard inference methods for multivariate, contrast-based meta-analysis models, but recent studies have revealed the resultant confidence intervals of average…
Descriptors: Network Analysis, Meta Analysis, Regression (Statistics), Error of Measurement
Riley, Richard D.; Collins, Gary S.; Hattle, Miriam; Whittle, Rebecca; Ensor, Joie – Research Synthesis Methods, 2023
Before embarking on an individual participant data meta-analysis (IPDMA) project, researchers should consider the power of their planned IPDMA conditional on the studies promising their IPD and their characteristics. Such power estimates help inform whether the IPDMA project is worth the time and funding investment, before IPD are collected. Here,…
Descriptors: Computation, Meta Analysis, Participant Characteristics, Data
Wang, Chia-Chun; Lee, Wen-Chung – Research Synthesis Methods, 2019
A systematic review and meta-analysis is an important step in evidence synthesis. The current paradigm for meta-analyses requires a presentation of the means under a random-effects model; however, a mean with a confidence interval provides an incomplete summary of the underlying heterogeneity in meta-analysis. Prediction intervals show the range…
Descriptors: Meta Analysis, Computation, Statistical Analysis, Prediction
Günhan, Burak Kürsad; Friede, Tim; Held, Leonhard – Research Synthesis Methods, 2018
Network meta-analysis (NMA) is gaining popularity for comparing multiple treatments in a single analysis. Generalized linear mixed models provide a unifying framework for NMA, allow us to analyze datasets with dichotomous, continuous or count endpoints, and take into account multiarm trials, potential heterogeneity between trials and network…
Descriptors: Meta Analysis, Regression (Statistics), Statistical Inference, Probability
Jackson, Dan; Bowden, Jack; Baker, Rose – Research Synthesis Methods, 2015
Moment-based estimators of the between-study variance are very popular when performing random effects meta-analyses. This type of estimation has many advantages including computational and conceptual simplicity. Furthermore, by using these estimators in large samples, valid meta-analyses can be performed without the assumption that the treatment…
Descriptors: Meta Analysis, Hierarchical Linear Modeling, Computation, Evaluation Methods
