NotesFAQContact Us
Collection
Advanced
Search Tips
Showing all 6 results Save | Export
Using PyMOL to Explore the Effects of ph on Noncovalent Interactions between Immunoglobulin G and Protein A: A Guided-Inquiry Biochemistry Activity
Peer reviewed Peer reviewed
Direct linkDirect link
Roche Allred, Zahilyn D.; Tai, Heeyoung; Bretz, Stacey Lowery; Page, Richard C. – Biochemistry and Molecular Biology Education, 2017
Students' understandings of foundational concepts such as noncovalent interactions, pH and pK[subscript a] are crucial for success in undergraduate biochemistry courses. We developed a guided-inquiry activity to aid students in making connections between noncovalent interactions and pH/pK[subscript a]. Students explore these concepts by examining…
Descriptors: Biochemistry, Science Instruction, Undergraduate Students, Interaction
Iodine Coulometry of Various Reducing Agents Including Thiols with Online Photocell Detection Coupled to a Multifunctional Chemical Analysis Station to Eliminate Student End Point Detection by Eye
Peer reviewed Peer reviewed
Direct linkDirect link
Padilla Mercado, Jeralyne B.; Coombs, Eri M.; De Jesus, Jenny P.; Bretz, Stacey Lowery; Danielson, Neil D. – Journal of Chemical Education, 2018
Multifunctional chemical analysis (MCA) systems provide a viable alternative for large scale instruction while supporting a hands-on approach to more advanced instrumentation. These systems are robust and typically use student stations connected to a remote central computer for data collection, minimizing the need for computers at every student…
Descriptors: Chemistry, Science Education, Hands on Science, Scientific Concepts
Trispyrazolylborate Complexes: An Advanced Synthesis Experiment Using Paramagnetic NMR, Variable-Temperature NMR, and EPR Spectroscopies
Peer reviewed Peer reviewed
Direct linkDirect link
Abell, Timothy N.; McCarrick, Robert M.; Bretz, Stacey Lowery; Tierney, David L. – Journal of Chemical Education, 2017
A structured inquiry experiment for inorganic synthesis has been developed to introduce undergraduate students to advanced spectroscopic techniques including paramagnetic nuclear magnetic resonance and electron paramagnetic resonance. Students synthesize multiple complexes with unknown first row transition metals and identify the unknown metals by…
Descriptors: Inorganic Chemistry, Undergraduate Students, Laboratory Procedures, Laboratory Experiments
Visualizing Molecular Chirality in the Organic Chemistry Laboratory Using Cholesteric Liquid Crystals
Peer reviewed Peer reviewed
Direct linkDirect link
Popova, Maia; Bretz, Stacey Lowery; Hartley, C. Scott – Journal of Chemical Education, 2016
Although stereochemistry is an important topic in second-year undergraduate organic chemistry, there are limited options for laboratory activities that allow direct visualization of macroscopic chiral phenomena. A novel, guided-inquiry experiment was developed that allows students to explore chirality in the context of cholesteric liquid crystals.…
Descriptors: Visualization, Molecular Structure, Teaching Methods, Organic Chemistry
What Is the True Color of Fresh Meat? A Biophysical Undergraduate Laboratory Experiment Investigating the Effects of Ligand Binding on Myoglobin Using Optical, EPR, and NMR Spectroscopy
Peer reviewed Peer reviewed
Direct linkDirect link
Linenberger, Kimberly; Bretz, Stacey Lowery; Crowder, Michael W.; McCarrick, Robert; Lorigan, Gary A.; Tierney, David L. – Journal of Chemical Education, 2011
With an increased focus on integrated upper-level laboratories, we present an experiment integrating concepts from inorganic, biological, and physical chemistry content areas. Students investigate the effects of ligand strength on the spectroscopic properties of the heme center in myoglobin using UV-vis, [superscript 1]H NMR, and EPR…
Descriptors: Inorganic Chemistry, Biology, Physics, Chemistry
A Guided Inquiry Experiment for the Measurement of Activation Energies in the Biophysical Chemistry Laboratory: Decarboxylation of Pyrrole-2-Carboxylate
Peer reviewed Peer reviewed
Direct linkDirect link
Hutchinson, Kelly M.; Bretz, Stacey Lowery; Mettee, Howard D.; Smiley, Jeffrey A. – Biochemistry and Molecular Biology Education, 2005
A laboratory experiment for undergraduate biophysical chemistry is described, in which the acid concentration and temperature dependences of the decarboxylation of pyrrole-2-carboxylate are measured using a continuous ultraviolet (UV) spectrophotometric assay. Data collection and analysis are structured using principles of guided inquiry. Data…
Descriptors: Laboratory Experiments, Chemistry, College Science, Undergraduate Students