Studies have shown that many Hispanic/Latino youth can be considered at high risk for substance abuse problems. The rapidly increasing numbers of Hispanic American youth and the multiple antecedent risk factors suggest that substance abuse prevention must be a leading priority in the Hispanic/Latino communities. Information is a primary tool in understanding the nature of substance abuse problems and effective prevention. This Resource Guide provides information and referrals to help prevention specialists, educators, and community leaders better meet the needs of the Hispanic/Latino community. The first section lists 25 prevention materials, ranging from brochures for adults to classroom materials. Many are available in Spanish. The second section contains abstracts of 61 studies, articles, and research reports on prevention and treatment and prevalence and patterns of use. The third section lists 28 organizations, groups, and programs that can provide information or assistance. The final section lists 20 Internet access sites, some maintained by the Federal Government, where information can be obtained about Hispanic Americans and substance abuse. (SLD)