Implementation of multi-tier system of supports (MTSS) has grown rapidly in Kansas and is a key strategy for turning around low-performing schools in the state. MTSS is designed to improve outcomes for all students by instituting system-level change across the classroom, school, district, and state. Such systemic change is accomplished by developing a coherent continuum of evidence-based, systemwide practices to support a rapid response to each student's academic and behavioral needs. MTSS features frequent data-based monitoring for instructional decision making. MTSS core components include evidence-based curricula, high-quality instruction, a comprehensive assessment system, data-based decision making, effective intervention, fidelity of implementation, ongoing professional development, and leadership within an empowering school and district culture. This final summative evaluation report: (1) Describes the current status of MTSS implementation in Kansas; (2) Provides insights as to what it takes to implement MTSS with fidelity Offers recommendations for next steps; and (3) Offers recommendations for next steps. The evaluation team, led by WestEd's Kristin Reedy and Natalie Lacireno-Paquet, found that Kansas MTSS is substantially contributing to improved student outcomes at the local level, as well as benefitting teachers, improving instruction, and supporting better school functioning. Appended are: (1) Evaluation Methods; (2) Kansas MTSS School Survey of Effective Instructional Practices Summary, 2014; (3) Analysis of Kansas MTSS School Survey of Effective Instructional Practices, by Stages of Implementation; and (4) Infographic: MTSS Implementation: What does it take? [For the evaluation brief of this report see ED559728.]