This document outlines the content standards for science in the state of Colorado. The document is organized into six standards, each of which is subdivided into a set of guiding questions exemplifying the standard and a series of lists defining what is expected of students at each grade level within the standard. The standards are that students understand the process of scientific investigation; that they know and understand qualities of matter and energy; that they know and understand the characteristics and structures of living things; that they know and understand the processes and interactions of Earth's systems; that they know and understand interrelationships between science, technology, and human activity; and that they understand that science involves a particular way of knowing. A list of references is also included. (MM)