When designing cluster-randomized trials (CRTs), one important consideration is determining the proper sample sizes across levels and treatment conditions to cost-efficiently achieve adequate statistical power. This consideration is usually addressed in an optimal design framework by leveraging the cost structures of sampling and optimizing the…

Cluster-randomized trials have been widely used to evaluate the treatment effects of interventions on student outcomes. When interventions are implemented by teachers, researchers need to account for the nested structure in schools (i.e., students are nested within teachers nested within schools). Schools usually have a very limited number of…

Psychologists are emphasizing the importance of predictive conclusions. Machine learning methods, such as supervised neural networks, have been used in psychological studies as they naturally fit prediction tasks. However, we are concerned about whether neural networks fitted with random datasets (i.e., datasets where there is no relationship…

Random encouragement designs evaluate treatments that aim to increase participation in a program or activity. These randomized controlled trials (RCTs) can also assess the mediated effects of participation itself on longer term outcomes using a complier average causal effect (CACE) estimation framework. This article considers power analysis…

Multisite cluster randomized trials (MCRTs), in which, the intermediate-level clusters (e.g., classrooms) are randomly assigned to the treatment or control condition within each site (e.g., school), are among the most commonly used experimental designs across a broad range of disciplines. MCRTs often align with the theory that programs are…

Cluster randomized trials (CRTs) are commonly used to evaluate the causal effects of educational interventions, where the entire clusters (e.g., schools) are randomly assigned to treatment or control conditions. This study introduces statistical methods for designing and analyzing two-level (e.g., students nested within schools) and three-level…

Practitioners and policymakers often want estimates of the effect of an intervention for their local community, e.g., region, state, county. In the ideal, these multiple population average treatment effect (ATE) estimates will be considered in the design of a single randomized trial. Methods for sample selection for generalizing the sample ATE to…

Optimal design of multisite randomized trials leverages sampling costs to optimize sampling ratios and ultimately identify more efficient and powerful designs. Past implementations of the optimal design framework have assumed that costs of sampling units are equal across treatment conditions. In this study, we developed a more flexible optimal…

In two-level designs, the total sample is a function of both the number of Level 2 clusters and the average number of Level 1 units per cluster. Traditional multilevel power calculations rely on either the arithmetic average or the harmonic mean when estimating the average number of Level 1 units across clusters of unbalanced size. The current…

Comprehensive evaluation of treatment effects is aided by considerations for moderated effects. In educational research, the combination of natural hierarchical structures and prevalence of group-administered or shared facilitator treatments often produces three-level partially nested data structures. Literature details planning strategies for a…

Before embarking on an individual participant data meta-analysis (IPDMA) project, researchers should consider the power of their planned IPDMA conditional on the studies promising their IPD and their characteristics. Such power estimates help inform whether the IPDMA project is worth the time and funding investment, before IPD are collected. Here,…

The meta-analytic-predictive (MAP) approach is a Bayesian method to incorporate historical controls in new trials that aims to increase the statistical power and reduce the required sample size. Here we investigate how to calculate the sample size of the new trial when historical data is available, and the MAP approach is used in the analysis. In…

Optimal sampling frameworks attempt to identify the most efficient sampling plans to achieve an adequate statistical power. Although such calculations are theoretical in nature, they are critical to the judicious and wise use of funding because they serve as important starting points that guide practical discussions around sampling tradeoffs and…

In cluster randomized evaluations, a treatment or intervention is randomly assigned to a set of clusters each with constituent individual units of observations (e.g., student units that attend schools, which are assigned to treatment). One consideration of these designs is how many units are needed per cluster to achieve adequate statistical…

Cluster randomized control trials often incorporate a longitudinal component where, for example, students are followed over time and student outcomes are measured repeatedly. Besides examining how intervention effects induce changes in outcomes, researchers are sometimes also interested in exploring whether intervention effects on outcomes are…