Meta-analysis is a useful tool in clinical research, as it combines the results of multiple clinical studies to improve precision when answering a particular scientific question. While there has been a substantial increase in publications using meta-analysis in various clinical research topics, the number of published meta-analyses in metabolomics…

When meta-analyzing heterogeneous bodies of literature, meta-regression can be used to account for potentially relevant between-studies differences. A key challenge is that the number of candidate moderators is often high relative to the number of studies. This introduces risks of overfitting, spurious results, and model non-convergence. To…

The purpose of this research was to compare the performances of the Fixed Effect Model (FEM) and the Random Effects Model (REM) in the meta-analysis studies conducted through 5, 10, 20 and 40 studies with an outlier and 4, 9, 19 and 39 studies without an outlier in terms of estimated common effect size, confidence interval coverage rate and…

Computer programming is regarded as an important skill for the future. However, many K-12 students face challenges and difficulties in learning traditional text-based programming. Block-based visual programming (BVP) can reduce the difficulty of learning programming and is seen as a potential programming education tool. Nevertheless, the effects…