Objective: To identify predictors of meningococcal vaccine uptake among university and college students, the most common carriers of meningococcal disease. Participants: University or college students aged 18 to 25 years. Methods: Multiple databases, citations, and gray literature were systematically searched in April 2017 and January 2019, for…

The general science of infection prevention and control can be applied to and adapted for a variety of settings, including kindergarten through grade 12 (K-12). Strategies can be implemented in the classroom and whole school environment to prevent a wide array of illnesses caused by both bacteria and viruses. This science brief presents findings…

Infection by pathogenic microbes initiates a set of complex interactions between the pathogen and the host mediated by pattern recognition receptors. Innate immune responses play direct roles in host defense during the early stages of infection, and they also exert a profound influence on the generation of the adaptive immune responses that ensue.…

In 2007, Sanofi Pasteur asked RAND Health, a division of the RAND Corporation, to study the current climate for adolescent immunization in the United States, to recommend broad strategies for immunizing low-income adolescents (through age 18), and to identify promising "on the ground" practices consistent with the proposed strategic…

This report presents information on the status of the safety and use of polio vaccines in the United States. Topics discussed include: (1) the role of the Food and Drug Administration (FDA) in processing an inactivated polio vaccine license application; (2) the steps the federal government has taken to improve the safety of the vaccine; (3) the…

Improvements in immunization levels and declines in disease incidence have been brought about effectively by the enactment and enforcement of immunization requirements for school-age children and military recruits. Colleges and universities should also institute immunization requirements as a condition of enrollment. (Authors/CJ)

This paper summarizes the major advances achieved by research in the fields of infectious diseases and immunizations during the 1970s, and delineates directions for future research in these fields. (Author/MP)

A survey is presented of recently published periodical literature in the field of vaccine-preventable diseases. Information is provided on writings about: (1) measles; (2) rubella; (3) influenza; (4) diphtheria-pertussis-tetanus; and (5) other vaccine-preventable diseases. For each disease general information is covered, as well as clinical and…

This article reviews studies linking autistic disorder with various immune factors. It concludes that although various immune system abnormalities have been reported in children with autism, previous studies are largely association based and it remains difficult to draw conclusions regarding the role of immune factors in the etiopathogenesis of…

Terrorist acts and the fear of terrorism have become a part of everyday life in the early 21st century. Among the threats most feared is bioterrorism, including the intentional release of smallpox. With the invasion of Iraq and toppling of the Saddam Hussein regime, acute bioterrorism fears have abated; however, an ongoing threat remains. This…

Measured the impact of managed care on the utilization of preventive health-care services by 867 inner-city Los Angeles families and assessed the relationship between insurance type, source of care, and access to immunization services. Results show that, lacking financial incentives, managed care is unlikely to improve immunization rates among…

Selected for discussion are certain advances in basic research and technologic innovation which shape the past, present, and future of medical care. Included are infectious diseases, especially hepatitis, immunology, clinical disorders of the immune system and the histocompatability system. (Author/SA)

Discusses school health services, adolescent immunization, current school immunization practices, and support for school-based immunization programs. Children and adolescents can receive preventive health services, including immunizations and monitoring of immunization levels. Expanding school health services could improve the immunization levels…

Despite the effectiveness of vaccinations in preventing disease, preschool children, particularly in the inner cities, are not being adequately immunized. Inadequate clinic staff and hours, inconvenient locations, prohibitive policies, and missed opportunities within the health care system may contribute to this problem. Suggests policy changes…

Intended as a companion piece to volume 1 in the Methods Series, Communicable Disease Control Planing (CE 024 229), this first of six volumes in the International Health Planning Reference Series is a combined literature review and annotated bibliography dealing with communicable disease control in developing countries. The review identifies…