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Direct linkWeibel, Stephanie; Popp, Maria; Reis, Stefanie; Skoetz, Nicole; Garner, Paul; Sydenham, Emma – Research Synthesis Methods, 2023
Evidence synthesis findings depend on the assumption that the included studies follow good clinical practice and results are not fabricated or false. Studies which are problematic due to scientific misconduct, poor research practice, or honest error may distort evidence synthesis findings. Authors of evidence synthesis need transparent mechanisms…
Descriptors: Identification, Randomized Controlled Trials, Integrity, Evaluation Methods
Seo, Michael; Furukawa, Toshi A.; Karyotaki, Eirini; Efthimiou, Orestis – Research Synthesis Methods, 2023
Clinical prediction models are widely used in modern clinical practice. Such models are often developed using individual patient data (IPD) from a single study, but often there are IPD available from multiple studies. This allows using meta-analytical methods for developing prediction models, increasing power and precision. Different studies,…
Descriptors: Prediction, Models, Patients, Data Analysis
Babic, Andrija; Poklepovic Pericic, Tina; Pieper, Dawid; Puljak, Livia – Research Synthesis Methods, 2020
Background: It is challenging to keep systematic reviews (SR) current and updated. Cochrane designated some of its SRs as "stable," that is, not in need of updating. The issue of stabilizing an SR is an important in research synthesis, because it could help reduce research waste. The aim of this study was to analyze publicly available…
Descriptors: Literature Reviews, Research Problems, Synthesis, Evidence
Stoll, Carolyn R. T.; Izadi, Sonya; Fowler, Susan; Green, Paige; Suls, Jerry; Colditz, Graham A. – Research Synthesis Methods, 2019
Background: Although dual independent review of search results by two reviewers is generally recommended for systematic reviews, there are not consistent recommendations regarding the timing of the use of the second reviewer. This study compared the use of a complete dual review approach, with two reviewers in both the title/abstract screening…
Descriptors: Literature Reviews, Researchers, Research Problems, Research Methodology
Nejstgaard, Camilla Hansen; Lundh, Andreas; Abdi, Suhayb; Clayton, Gemma; Gelle, Mustafe Hassan Adan; Laursen, David Ruben Teindl; Olorisade, Babatunde Kazeem; Savovic, Jelena; Hróbjartsson, Asbjørn – Research Synthesis Methods, 2022
Randomised trials are often funded by commercial companies and methodological studies support a widely held suspicion that commercial funding may influence trial results and conclusions. However, these studies often have a risk of confounding and reporting bias. The risk of confounding is markedly reduced in meta-epidemiological studies that…
Descriptors: Medical Research, Randomized Controlled Trials, Corporations, Financial Support
Spineli, Loukia M.; Pandis, Nikolaos; Salanti, Georgia – Research Synthesis Methods, 2015
Objectives: The purpose of the study was to provide empirical evidence about the reporting of methodology to address missing outcome data and the acknowledgement of their impact in Cochrane systematic reviews in the mental health field. Methods: Systematic reviews published in the Cochrane Database of Systematic Reviews after January 1, 2009 by…
Descriptors: Mental Health, Literature Reviews, Data Analysis, Meta Analysis
