This unique document is a training manual for individuals such as job coaches and janitorial crew supervisors who train and work with Developmentally Disabled (DD) workers in vocational classrooms and on job sites. These workers need to be taught the importance of safety in the workplace using methods appropriate to their developmental needs. The manual uses visual icons and graphics for teaching (1) safe handling procedures for hazardous chemicals; (2) the use of protective equipment to prevent exposure to hazardous chemicals; and (3) prevention of accidents involving the use of potentially dangerous chemicals. The first chapter contains an overview of the training and suggested teaching methods. Chapter 2 provides background information based on Occupational Safety and Health Administration (OSHA) guidelines for safeguarding the health of workers. Chapter 3 contains teaching modules focused on meeting the special learning needs of each student. The document contains many graphics and visual icons to assist DD students in recognizing and memorizing protective equipment, types of hazards, routes of entry into the body, target organs, and emergency response measures. Appendices contain a worker checklist, student worksheets, and certificates for attendance and completion of the course.